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Series GSE250519 Query DataSets for GSE250519
Status Public on Jan 24, 2024
Title A mucus production programme promotes classical pancreatic ductal adenocarcinoma
Organisms Homo sapiens; Mus musculus
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary CUT&RUN for IgG, H3K4me3 and HA-SPDEF in human PDA HPAF-II cells and CUT&RUN HA-Spdef in murine KPC 2D FC1245 cells

We performed CUT&RUN assay in human and murine PDA cells to profile the direct binding of SPDEF to target genes.
 
Overall design Mapping of SPDEF binding sites in human and murine PDA cells.
 
Contributor(s) Tuveson DA, Tonelli C, Klingbeil O
Citation(s) 38262672
NIH grant(s)
Grant ID Grant title Affiliation Name
P30 CA045508 CSHL Cancer Center Support Grant COLD SPRING HARBOR LABORATORY David A Tuveson
S10 OD028632 Graphical Processing Units and a Large-Memory Compute Node for Applications in Genomics, Neuroscience, and Structural Biology COLD SPRING HARBOR LABORATORY Adam Charles Siepel
Submission date Dec 18, 2023
Last update date Jan 25, 2024
Contact name Olaf Klingbeil
E-mail(s) klingbe@cshl.edu
Organization name Cold Spring Harbor Laboratory
Street address 1 Bungtown Road
City Cold Spring Harbor
State/province New York
ZIP/Postal code 11724
Country USA
 
Platforms (2)
GPL18573 Illumina NextSeq 500 (Homo sapiens)
GPL19057 Illumina NextSeq 500 (Mus musculus)
Samples (12)
GSM7980842 HPAF-II_HA-hSPDEF_H3K4me3
GSM7980843 HPAF-II_HA-hSPDEF_HA_REP1
GSM7980844 HPAF-II_HA-hSPDEF_HA_REP2
Relations
BioProject PRJNA1054225

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE250519_GATA6_peaks.bed.gz 89.1 Kb (ftp)(http) BED
GSE250519_RAW.tar 1.0 Gb (http)(custom) TAR (of BW)
GSE250519_SPDEF_peaks.bed.gz 23.7 Kb (ftp)(http) BED
GSE250519_mSpdef_peaks.bed.gz 48.8 Kb (ftp)(http) BED
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