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Series GSE25147 Query DataSets for GSE25147
Status Public on Jan 12, 2011
Title Changes in gene expression in MKN45 cells in response to Helicobacter pylori lipopolysaccharide
Organism Homo sapiens
Experiment type Expression profiling by array
Summary This study set out to identify global changes in gene expression in MKN45 gastric epithelial cells following 8 hours stimulation with 10 μg/ml lipopolysaccharide (LPS) from the gastric pathogen H. pylori.
Microarray analysis was used to compare changes in gene expression between cells treated with 10 μg/ml H. pylori LPS and untreated cells at the same time point.
Overall design Total RNA was harvested from MKN45 cells following treatment with LPS for 8h or untreated cells at the same time-point. 2 independent experiments were carried out. RNA was labeled and hybridized to GeneChips to analyse changes in gene expression.
Contributor(s) Smith SM, Moran AP, Duggan SP, Kelleher DP
Citation(s) 21220698
Submission date Nov 04, 2010
Last update date Mar 25, 2019
Contact name Sinead Marian Smith
Organization name Trinity College Dublin
Lab Trinity Centre for Health Sciences
Street address St. James's Hospital
City Dublin 8
ZIP/Postal code D8
Country Ireland
Platforms (1)
GPL570 [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Samples (4)
GSM618013 MKN45 untreated rep 1
GSM618014 MKN45 untreated rep 2
GSM618015 MKN45 treated rep 1
This SubSeries is part of SuperSeries:
GSE25155 Tribbles 3 - a novel regulator of TLR2-mediated signaling in response to Helicobacter pylori lipopolysaccharide
BioProject PRJNA142771

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE25147_RAW.tar 22.0 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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