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Series GSE252249 Query DataSets for GSE252249
Status Public on May 21, 2024
Title m6A-mRNA&lncRNA Epitranscriptomic Microarray analysis for human liver tissues of healthy, HBV-infected with and without cirrhosis donors.
Organism Homo sapiens
Experiment type Expression profiling by array
Non-coding RNA profiling by array
Summary The samples of human liver tissues from the healthy donors, the HBV-infected patients without cirrhosis, and the HBV-infected patients with cirrhosis were collected. The tissues were then analyzed by the m6A-mRNA&lncRNA Epitranscriptomic miroarray. The Goal of this experiment was to determine the different of gene expression and m6a methylation of liver tissues among the healthy donors, the HBV-infected patients with and without cirrhosis.
Overall design a total of 9 liver tissues from different donors were collected, including 3 from healthy donors, 3 from HBV-infected patients without cirrohsis, and 3 from HBV-infected patients with cirrhosis. The total RNA were extracted from the tissues within 24h at 4 °C and ahead of microarray analysis. Ethical approval for this study was provided by the Ethical Committee of the Second Affiliated Hospital of Air Force Military Medical University, Xi’an, China on 24 February 2016. All research was conducted in accordance with both the Declarations of Helsinki and Istanbul. Written consent was given in writing by all subjects.
Contributor(s) Fan CJ
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Submission date Dec 29, 2023
Last update date May 22, 2024
Contact name Chao Fan
Organization name The Fourth Military Medical University
Street address #169, Changle Road, Xincheng District
City Xi'an
ZIP/Postal code 710032
Country China
Platforms (1)
GPL25759 Agilent-085753 Arraystar Human Epitranscriptomic microarray
Samples (9)
GSM7998001 liver tissues from the healthy donors 1
GSM7998002 liver tissues from the healthy donors 2
GSM7998003 liver tissues from the healthy donors 3
BioProject PRJNA1059006

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE252249_Matrix.xlsx 6.1 Mb (ftp)(http) XLSX
GSE252249_RAW.tar 52.5 Mb (http)(custom) TAR (of TXT)
Raw data provided as supplementary file
Processed data are available on Series record

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