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Series GSE252801 Query DataSets for GSE252801
Status Public on Jan 15, 2024
Title Gene expression profiling of human fibroblast MRC5 cells exposed to cigarette smoke condensate (CSC)
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Smoking is the main risk factor for many lung diseases including chronic obstructive pulmonary disease. Cigarette smoke (CS) contains carcinogenic and reactive oxygen species that favor DNA mutations and perturb the homeostasis and environment of cells. CS induces lung cell senescence resulting in a stable proliferation arrest and a senescence-associated secretory phenotype. It was recently reported that senescent cell accumulation promotes several lung diseases.
Overall design Normal human fibroblast cells (MRC5) were cultured with or without Cigarette Smoke Condensate
Contributor(s) Flaman J, Palazzo A, Bernard D
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Submission date Jan 09, 2024
Last update date Jan 15, 2024
Contact name jean-michel flaman
Phone +33687477812
Organization name Inserm 1052
Department CRCL
Street address 28 rue Laennec
City Lyon
ZIP/Postal code 69373
Country France
Platforms (1)
GPL13497 Agilent-026652 Whole Human Genome Microarray 4x44K v2 (Probe Name version)
Samples (6)
GSM8008011 MRC5_CSC_R1
GSM8008012 MRC5_CSC_R2
GSM8008013 MRC5_CSC_R3
BioProject PRJNA1062738

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE252801_RAW.tar 12.9 Mb (http)(custom) TAR (of TXT)

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