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| Status |
Public on Feb 02, 2012 |
| Title |
Microarray profiling of monocytic differentiaion reveals miRNA-mRNA intrinsic correlation (gene expression) |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Since the expression profile of miRNAs is specific in different tissues or under different physiological conditions, the correlations between miRNAs and mRNAs could vary under different biological circumstances. This is a study also used expression profiles of miRNA and mRNA during monocytic differentiation to explore the correlations between the expression levels of miRNAs and mRNA, either negative or positive.
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| Overall design |
After treatment of TPA, U937 cells present functional differentiation markers as well as specific cell morphology, which were confirmed by flow cytometric analysis and Wright-Giemsa staining.Here we use genome-wide microarray analysis to profile the expression levels of mRNA in normal U937 cells and differentiated U937 cells. For each differentiated and control sample, two hybridizations were performed by using a reversal fluorescent strategy.
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| Contributor(s) |
Wang J, Zhou Y |
| Citation(s) |
21538479 |
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| Submission date |
Dec 30, 2010 |
| Last update date |
Jan 18, 2013 |
| Contact name |
jing wang |
| E-mail(s) |
jwang.tsinghua@gmail.com
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| Organization name |
Medical Systems Biology Research Center School of Medicine Tsinghua University
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| Street address |
Tsinghu University
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| City |
Beijing |
| ZIP/Postal code |
100084 |
| Country |
China |
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| Platforms (1) |
| GPL8380 |
Capitalbio 22K Human oligo array version 1.0 |
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| Samples (2) |
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| This SubSeries is part of SuperSeries: |
| GSE26379 |
Microarray profiling of monocytic differentiaion reveals miRNA-mRNA intrinsic correlation |
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| Relations |
| BioProject |
PRJNA142277 |
