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Series GSE264223 Query DataSets for GSE264223
Status Public on Apr 20, 2024
Title lncRNA profile of CAFs isolated from Pancreatic cancer
Organism Homo sapiens
Experiment type Non-coding RNA profiling by high throughput sequencing
Summary Perineural invasion (PNI) is a unique biological feature of pancreatic cancer and is a key cause of pancreatic cancer metastasis, recurrence and poor postoperative survival, but its mechanism is largely unclarified. Clinical sample analysis and endoscopic ultrasonographic elasticity scoring indicated that cancer-associated fibroblasts (CAFs) are closely related to the occurrence of PNI. Furthermore, CAF-derived extracellular vesicles played an extremely important role in PNI in a dorsal root ganglion (DRG) coculture model and sciatic nerve model. To explore the lncRNA packaged in CAFs EVs, we conducted the lncRNA profile of CAFs isolated from pancreatic cancer
Overall design CAFs were isolated from pancreatic cancer and collected for lncRNA-seq.
Contributor(s) Zheng S, Hu C, Zhou Y, Chen R
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Submission date Apr 17, 2024
Last update date Apr 20, 2024
Contact name Chonghui Hu
Organization name Guangdong Provincial People’s Hospital
Street address NA Zhongshan 2nd Road, Guangzhou
City Guangzhou
ZIP/Postal code 5100080
Country China
Platforms (1)
GPL24676 Illumina NovaSeq 6000 (Homo sapiens)
Samples (6)
GSM8214632 NFs-rep1
GSM8214633 NFs-rep2
GSM8214634 NFs-rep3
BioProject PRJNA1101497

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Supplementary file Size Download File type/resource
GSE264223_lncRNA_All_gene_expression_count.txt.gz 676.1 Kb (ftp)(http) TXT
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