|
| Status |
Public on May 14, 2024 |
| Title |
FBXO5 degrades DOK6 to enhance cell mechanics and sensitivity to Temozolomide |
| Organism |
Homo sapiens |
| Experiment type |
Other
|
| Summary |
stable CRISPR/Cas9 sgRNA-expression U251 cells were treated with 200nM or 1500nM temozolomide for 72 hours, and then, we screened temozolomide-resistance genes by negative selection and temozolomide-sensitive genes by positive selection
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| |
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| Overall design |
Examination of differentially expressed sgRNAs in nagative group and positive group with control.
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| |
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| Contributor(s) |
Wang C, Wang M |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
May 10, 2024 |
| Last update date |
May 14, 2024 |
| Contact name |
Zhiqiang Liu |
| E-mail(s) |
zhiqiangliu@tmu.edu.cn
|
| Organization name |
Tianjin Medical University
|
| Department |
Pathophysiology
|
| Street address |
22 Qixiangtai Rd
|
| City |
Tianjin |
| ZIP/Postal code |
300070 |
| Country |
China |
| |
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| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
| Samples (9)
|
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| Relations |
| BioProject |
PRJNA1110241 |
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