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Series GSE27 Query DataSets for GSE27
Status Public on Feb 12, 2002
Title Sporulation in yeast
Organism Saccharomyces cerevisiae
Experiment type Expression profiling by array
Summary Diploid cells of budding yeast produce haploid cells through the developmental program of sporulation, which consists of meiosis and spore morphogenesis. DNA microarrays containing nearly every yeast gene were used to assay changes in gene expression during sporulation. At least seven distinct temporal patterns of induction were observed. The transcription factor Ndt80 appeared to be important for induction of a large group of genes at the end of meiotic prophase. Consensus sequences known or proposed to be responsible for temporal regulation could be identified solely from analysis of sequences of coordinately expressed genes. The temporal expression pattern provided clues to potential functions of hundreds of previously uncharacterized genes, some of which have vertebrate homologs that may function during gametogenesis.
This study is described in more detail in Chu S, et al. 1998. Science 282:699-705
Keywords: time-course
Contributor(s) Chu S, DeRisi J, Eisen MB, Mulholland J, Botstein D, Brown PO, Herskowitz I
Citation(s) 9784122
Submission date Feb 08, 2002
Last update date Jan 18, 2013
Organization Stanford Microarray Database (SMD)
Phone 650-498-6012
Department Stanford University, School of Medicine
Street address 300 Pasteur Drive
City Stanford
State/province CA
ZIP/Postal code 94305
Country USA
Platforms (1)
GPL67 yeast_v1_2.2
Samples (7)
GSM992 Sporulation t0
GSM993 Sporulation t2hrs
GSM994 Sporulation t5hrs
BioProject PRJNA84695

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