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Series GSE27253 Query DataSets for GSE27253
Status Public on Jun 17, 2011
Title Analysis of the impact of cellular miRNA signatures on the profiles of circulating miRNA biomarkers (variability data)
Platform organism synthetic construct
Sample organism Homo sapiens
Experiment type Non-coding RNA profiling by array
Summary Circulating miRNAs are an emerging class of biomarkers correlating their specific expression patterns to disease states. A considerable proportion of hematopoietically-derived miRNAs are present in plasma with the ability to confound the signature of true circulating miRNA species. We use microarray analysis to catalogue a list of 313 haemotopoetic miRNAs and analyze expression profiles of cell-free miRNAs in individual plasma fractions after calibraiting for cellular miRNA signals. Comprehensive global maps of bona fide circulating miRNA species are presented, and inter-individual varibility and gender-specific expession is explored in populations of healthy individuals.
 
Overall design Supernatant 1 (S1) fractions from 8 male and 10 female individuals.
 
Contributor(s) Duttagupta R, Jiang R, Getts RC, Gollub J, Jones KW
Citation(s) 21698099
Submission date Feb 11, 2011
Last update date May 02, 2017
Contact name Radha Duttagupta
E-mail(s) Radharani_Duttagupta@affymetrix.com
Phone 408-731-5691
Fax 408-731-5463
Organization name Affymetrix
Department Applied Research
Street address 3450 Central Expressway
City Santa Clara
State/province CA
ZIP/Postal code 95051
Country USA
 
Platforms (1)
GPL8786 [miRNA-1] Affymetrix Multispecies miRNA-1 Array
Samples (18)
GSM673791 Male_rep1
GSM673792 Male_rep2
GSM673793 Male_rep3
This SubSeries is part of SuperSeries:
GSE27256 Impact of cellular miRNAs on the biomarker signatures of circulating miRNAs
Relations
BioProject PRJNA141827

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE27253_RAW.tar 2.7 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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