 |
 |
GEO help: Mouse over screen elements for information. |
|
| Status |
Public on Aug 04, 2011 |
| Title |
Gene Expression Profiling of Fixed Tissues of Lymph Node Metastasis in Hepatocellular Carcinoma |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
RNA was extracted from formalin-fixed specimens of paired intratumoral and peritumoral tissues of patients with lymph node-positive (n=20) or negative (n=20) HCC. A cDNA-mediated annealing, selection, extension, and ligation assay was performed with an array of 502 known cancer-related genes to identify differentially expressed genes in 80 RNA samples.
|
| |
|
| Overall design |
Total RNA was purified from the tissue specimens using the High Pure RNA Paraffin Kit according to the manufacturer’s protocol. DASL experiments were performed to identify genes that were differentially expressed between the lymph node metastasis (LNM) and non-lymph node metastasis (NLNM) groups of matched intratumoral and peritumoral tissues by using A cDNA-mediated annealing, selection, extension, and ligation assay.
|
| |
|
| Contributor(s) |
Xiang Z, Zeng Z, Fan J, Tang Z, Zeng H, Gao D |
| Citation(s) |
21712445 |
| |
| Submission date |
Mar 29, 2011 |
| Last update date |
Mar 23, 2012 |
| Contact name |
Zuolin Xiang |
| E-mail(s) |
xzl815@sohu.com
|
| Organization name |
Zhongshan Hospital, Fudan University
|
| Street address |
136 Yi Xue Yuan Road
|
| City |
Shanghai |
| ZIP/Postal code |
200032 |
| Country |
China |
| |
|
| Platforms (1) |
| GPL5858 |
DASL Human Cancer Panel by Gene |
|
| Samples (80)
|
| GSM699172 |
peritumoral HCC, lymph node metastasis, patient 1 |
| GSM699173 |
intratumoral HCC, lymph node metastasis, patient 1 |
| GSM699174 |
peritumoral HCC, lymph node metastasis, patient 2 |
| GSM699175 |
intratumoral HCC, lymph node metastasis, patient 2 |
| GSM699176 |
peritumoral HCC, lymph node metastasis, patient 3 |
| GSM699177 |
intratumoral HCC, lymph node metastasis, patient 3 |
| GSM699178 |
peritumoral HCC, lymph node metastasis, patient 4 |
| GSM699179 |
intratumoral HCC, lymph node metastasis, patient 4 |
| GSM699180 |
peritumoral HCC, lymph node metastasis, patient 5 |
| GSM699181 |
intratumoral HCC, lymph node metastasis, patient 5 |
| GSM699182 |
peritumoral HCC, lymph node metastasis, patient 6 |
| GSM699183 |
intratumoral HCC, lymph node metastasis, patient 6 |
| GSM699184 |
peritumoral HCC, lymph node metastasis, patient 7 |
| GSM699185 |
intratumoral HCC, lymph node metastasis, patient 7 |
| GSM699186 |
peritumoral HCC, lymph node metastasis, patient 8 |
| GSM699187 |
intratumoral HCC, lymph node metastasis, patient 8 |
| GSM699188 |
peritumoral HCC, lymph node metastasis, patient 9 |
| GSM699189 |
intratumoral HCC, lymph node metastasis, patient 9 |
| GSM699190 |
peritumoral HCC, lymph node metastasis, patient 10 |
| GSM699191 |
intratumoral HCC, lymph node metastasis, patient 10 |
| GSM699192 |
peritumoral HCC, lymph node metastasis, patient 11 |
| GSM699193 |
intratumoral HCC, lymph node metastasis, patient 11 |
| GSM699194 |
peritumoral HCC, lymph node metastasis, patient 12 |
| GSM699195 |
intratumoral HCC, lymph node metastasis, patient 12 |
| GSM699196 |
peritumoral HCC, lymph node metastasis, patient 13 |
| GSM699197 |
intratumoral HCC, lymph node metastasis, patient 13 |
| GSM699198 |
peritumoral HCC, lymph node metastasis, patient 14 |
| GSM699199 |
intratumoral HCC, lymph node metastasis, patient 14 |
| GSM699200 |
peritumoral HCC, lymph node metastasis, patient 15 |
| GSM699201 |
intratumoral HCC, lymph node metastasis, patient 15 |
| GSM699202 |
peritumoral HCC, lymph node metastasis, patient 16 |
| GSM699203 |
intratumoral HCC, lymph node metastasis, patient 16 |
| GSM699204 |
peritumoral HCC, lymph node metastasis, patient 17 |
| GSM699205 |
intratumoral HCC, lymph node metastasis, patient 17 |
| GSM699206 |
peritumoral HCC, lymph node metastasis, patient 18 |
| GSM699207 |
intratumoral HCC, lymph node metastasis, patient 18 |
| GSM699208 |
peritumoral HCC, lymph node metastasis, patient 19 |
| GSM699209 |
intratumoral HCC, lymph node metastasis, patient 19 |
| GSM699210 |
peritumoral HCC, lymph node metastasis, patient 20 |
| GSM699211 |
intratumoral HCC, lymph node metastasis, patient 20 |
| GSM699212 |
peritumoral HCC, non-lymph node metastasis, patient 21 |
| GSM699213 |
intratumoral HCC, non-lymph node metastasis, patient 21 |
| GSM699214 |
peritumoral HCC, non-lymph node metastasis, patient 22 |
| GSM699215 |
intratumoral HCC, non-lymph node metastasis, patient 22 |
| GSM699216 |
peritumoral HCC, non-lymph node metastasis, patient 23 |
| GSM699217 |
intratumoral HCC, non-lymph node metastasis, patient 23 |
| GSM699218 |
peritumoral HCC, non-lymph node metastasis, patient 24 |
| GSM699219 |
intratumoral HCC, non-lymph node metastasis, patient 24 |
| GSM699220 |
peritumoral HCC, non-lymph node metastasis, patient 25 |
| GSM699221 |
intratumoral HCC, non-lymph node metastasis, patient 25 |
| GSM699222 |
peritumoral HCC, non-lymph node metastasis, patient 26 |
| GSM699223 |
intratumoral HCC, non-lymph node metastasis, patient 26 |
| GSM699224 |
peritumoral HCC, non-lymph node metastasis, patient 27 |
| GSM699225 |
intratumoral HCC, non-lymph node metastasis, patient 27 |
| GSM699226 |
peritumoral HCC, non-lymph node metastasis, patient 28 |
| GSM699227 |
intratumoral HCC, non-lymph node metastasis, patient 28 |
| GSM699228 |
peritumoral HCC, non-lymph node metastasis, patient 29 |
| GSM699229 |
intratumoral HCC, non-lymph node metastasis, patient 29 |
| GSM699230 |
peritumoral HCC, non-lymph node metastasis, patient 30 |
| GSM699231 |
intratumoral HCC, non-lymph node metastasis, patient 30 |
| GSM699232 |
peritumoral HCC, non-lymph node metastasis, patient 31 |
| GSM699233 |
intratumoral HCC, non-lymph node metastasis, patient 31 |
| GSM699234 |
peritumoral HCC, non-lymph node metastasis, patient 32 |
| GSM699235 |
intratumoral HCC, non-lymph node metastasis, patient 32 |
| GSM699236 |
peritumoral HCC, non-lymph node metastasis, patient 33 |
| GSM699237 |
intratumoral HCC, non-lymph node metastasis, patient 33 |
| GSM699238 |
peritumoral HCC, non-lymph node metastasis, patient 34 |
| GSM699239 |
intratumoral HCC, non-lymph node metastasis, patient 34 |
| GSM699240 |
peritumoral HCC, non-lymph node metastasis, patient 35 |
| GSM699241 |
intratumoral HCC, non-lymph node metastasis, patient 35 |
| GSM699242 |
peritumoral HCC, non-lymph node metastasis, patient 36 |
| GSM699243 |
intratumoral HCC, non-lymph node metastasis, patient 36 |
| GSM699244 |
peritumoral HCC, non-lymph node metastasis, patient 37 |
| GSM699245 |
intratumoral HCC, non-lymph node metastasis, patient 37 |
| GSM699246 |
peritumoral HCC, non-lymph node metastasis, patient 38 |
| GSM699247 |
intratumoral HCC, non-lymph node metastasis, patient 38 |
| GSM699248 |
peritumoral HCC, non-lymph node metastasis, patient 39 |
| GSM699249 |
intratumoral HCC, non-lymph node metastasis, patient 39 |
| GSM699250 |
peritumoral HCC, non-lymph node metastasis, patient 40 |
| GSM699251 |
intratumoral HCC, non-lymph node metastasis, patient 40 |
|
| Relations |
| BioProject |
PRJNA139579 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE28248_differential.txt.gz |
115.4 Kb |
(ftp)(http) |
TXT |
| GSE28248_non-normalized_data.txt.gz |
627.8 Kb |
(ftp)(http) |
TXT |
| Processed data included within Sample table |
| Processed data are available on Series record |
|
|
|
|
 |
Less...
More...