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| Status |
Public on Apr 02, 2011 |
| Title |
Genome-wide profiling of tumor cells in multiple myeloma |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
In multiple myeloma (MM), endothelial progenitor cells (EPCs) regulate tumor angiogenesis and disease progression. They share a common bone marrow microenvironment with myeloma tumor cells. CD138+ tumor plasma cells from 12 newly diagnosed patients with advanced MM were examined for genomic instability by RNA microarrays to assess changes in gene expression.
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| Overall design |
Tumor cells were derived from single-cell suspensions of bone marrow (BM) aspirates from newly diagnosed MM patients, and RNA was extracted for microarray hybridization.
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| Contributor(s) |
Batuman O, Braunstein M |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Apr 01, 2011 |
| Last update date |
Mar 25, 2019 |
| Contact name |
Olcay Batuman |
| Organization name |
SUNY Downstate Medical Center
|
| Street address |
450 Clarkson Ave, Box 20
|
| City |
Brooklyn |
| State/province |
NY |
| ZIP/Postal code |
11203 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
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| Samples (12)
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| This SubSeries is part of SuperSeries: |
| GSE28331 |
Genome-wide profiling of endothelial progenitor cells in multiple myeloma: disease-relevant pathways and genomic markers |
|
| Relations |
| BioProject |
PRJNA143213 |
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