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Series GSE28329 Query DataSets for GSE28329
Status Public on Apr 02, 2011
Title Genome-wide array comparative genomic hybridization (aCGH) profiling of endothelial progenitor cells, and their comparison to tumor plasma cells, in multiple myeloma
Organism Homo sapiens
Experiment type Genome variation profiling by genome tiling array
Summary In multiple myeloma (MM), endothelial progenitor cells (EPCs) regulate tumor angiogenesis and disease progression. EPCs from 16 newly diagnosed patients with advanced MM were examined for genomic instability by aCGH to assess chromosomal gains and losses. Data were compared to aCGH results from corresponding CD138+ tumor plasma cells from these patients.
 
Overall design EPCs and tumor cells were derived from single-cell suspensions of bone marrow (BM) aspirates from newly diagnosed MM patients, and total genomic DNA was extracted for aCGH. DNA from healthy male peripheral blood mononuclear cells (PBMCs; Promega, Madison, WI) was used as the normal control DNA.
 
Contributor(s) Batuman O, Braunstein M
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Submission date Apr 01, 2011
Last update date Oct 26, 2016
Contact name Olcay Batuman
Organization name SUNY Downstate Medical Center
Street address 450 Clarkson Ave, Box 20
City Brooklyn
State/province NY
ZIP/Postal code 11203
Country USA
 
Platforms (2)
GPL2873 Agilent-012750 Human Genome CGH Microarray 44A (Feature number version)
GPL4091 Agilent-014693 Human Genome CGH Microarray 244A (Feature number version)
Samples (32)
GSM700593 Myeloma EPC aCGH, 1
GSM700594 Myeloma EPC aCGH, 2
GSM700595 Myeloma EPC aCGH, 3
This SubSeries is part of SuperSeries:
GSE28331 Genome-wide profiling of endothelial progenitor cells in multiple myeloma: disease-relevant pathways and genomic markers
Relations
BioProject PRJNA143191

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE28329_EPC_aCGH.xls.gz 654.5 Kb (ftp)(http) XLS
GSE28329_RAW.tar 1.1 Gb (http)(custom) TAR (of TXT)
GSE28329_Tumor_aCGH.xls.gz 634.8 Kb (ftp)(http) XLS
Processed data included within Sample table
Processed data are available on Series record

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