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| Status |
Public on Jul 27, 2006 |
| Title |
No accelerated rate of protein evolution in male biased Drosophila pseudoobscura genes |
| Organism |
Drosophila pseudoobscura |
| Experiment type |
Expression profiling by SAGE
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| Summary |
Sexually dimorphic traits are subject to diversifying selection. Also genes with a male biased gene expression are probably affected by sexual selection and have a high rate of protein evolution. We used SAGE to measure sex biased gene expression in Drosophila pseudoobscura. Consistent with previous results from D. melanogaster, a larger number of genes were male biased (402 genes) than female biased (138 genes). About 34% of the genes changed the sex related expression pattern between D. melanogaster and D. pseudoobscura. Combining gene expression with protein divergence between both species, we observed a striking difference in rate of evolution for genes with a male biased gene expression in one species only. Contrary to expectations, D. pseudoobscura genes in this category showed no accelerated rate of protein evolution, while D. melanogaster genes did. If sexual selection is driving molecular evolution of male biased genes, our data imply a radically different selection regime in D. pseudoobscura.
Keywords: SAGE
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| Overall design |
Male and female SAGE libraries of D. pseudoobscura were developed for analyzing the gene expression pattern.
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| Contributor(s) |
Metta M, Gudavalli R, Gibert J, Schlötterer C |
| Citation(s) |
16816428 |
| |
| Submission date |
Jun 25, 2005 |
| Last update date |
Mar 16, 2012 |
| Contact name |
Schlötterer Christian |
| E-mail(s) |
christian.schloetterer@vu-wien.ac.at
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| Phone |
+43-1-25077-5603
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| Fax |
+43-1-25077-5693
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| Organization name |
Veterinärmedizinische Universität Wien
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| Department |
Institut für Tierzucht und Genetik
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| Street address |
Josef Baumann Gasse 1
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| City |
Wien |
| ZIP/Postal code |
A-1210 |
| Country |
Austria |
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| Platforms (1) |
| GPL2537 |
SAGE:10:NlaIII:Drosophila pseudoobscura |
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| Samples (2) |
| GSM60839 |
SAGE_Drosophila pseudoobscura_Male |
| GSM60840 |
SAGE_Drosophila pseudoobscura_Female |
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| Relations |
| BioProject |
PRJNA92475 |
