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Series GSE2840 Query DataSets for GSE2840
Status Public on Jul 27, 2006
Title No accelerated rate of protein evolution in male biased Drosophila pseudoobscura genes
Organism Drosophila pseudoobscura
Experiment type Expression profiling by SAGE
Summary Sexually dimorphic traits are subject to diversifying selection. Also genes with a male biased gene expression are probably affected by sexual selection and have a high rate of protein evolution. We used SAGE to measure sex biased gene expression in Drosophila pseudoobscura. Consistent with previous results from D. melanogaster, a larger number of genes were male biased (402 genes) than female biased (138 genes). About 34% of the genes changed the sex related expression pattern between D. melanogaster and D. pseudoobscura. Combining gene expression with protein divergence between both species, we observed a striking difference in rate of evolution for genes with a male biased gene expression in one species only. Contrary to expectations, D. pseudoobscura genes in this category showed no accelerated rate of protein evolution, while D. melanogaster genes did. If sexual selection is driving molecular evolution of male biased genes, our data imply a radically different selection regime in D. pseudoobscura.
Keywords: SAGE
Overall design Male and female SAGE libraries of D. pseudoobscura were developed for analyzing the gene expression pattern.
Contributor(s) Metta M, Gudavalli R, Gibert J, Schlötterer C
Citation(s) 16816428
Submission date Jun 25, 2005
Last update date Mar 16, 2012
Contact name Schlötterer Christian
Phone +43-1-25077-5603
Fax +43-1-25077-5693
Organization name Veterinärmedizinische Universität Wien
Department Institut für Tierzucht und Genetik
Street address Josef Baumann Gasse 1
City Wien
ZIP/Postal code A-1210
Country Austria
Platforms (1)
GPL2537 SAGE:10:NlaIII:Drosophila pseudoobscura
Samples (2)
GSM60839 SAGE_Drosophila pseudoobscura_Male
GSM60840 SAGE_Drosophila pseudoobscura_Female
BioProject PRJNA92475

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