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Status |
Public on Dec 26, 2024 |
Title |
Aberrantly Expressed RECQL4 Helicase Supports Proliferation and Drug Resistance of Human Glioma Cells and Glioma Stem Cells |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
RECQL4 depletion in human glioma cells with genetic tools slightly impaired cell viability and DNA replication, induced changes in gene expression and increased sensitivity of glioma cells and glioma stem cells to chemotherapeutics
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Overall design |
RecQL4 knock-out and wild type LN18 and LN229 cell lines were used to the experiments.
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Contributor(s) |
Krol SK, Kaczmarczyk A, Wojnicki K, Wojtas B, Gielniewski B, Grajkowska W, Kotulska K, Szczylik C, Czepko R, Banach M, Kaspera W, Szopa W, Marchel A, Czernicki T, Kaminska B |
Citation missing |
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Submission date |
Dec 20, 2024 |
Last update date |
Dec 26, 2024 |
Contact name |
Bartosz Wojtas |
E-mail(s) |
bartoszwojtas83@gmail.com
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Phone |
692156006
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Organization name |
Nencki Institute of Experimental Biology
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Street address |
Pasteura 3
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City |
Warsaw |
ZIP/Postal code |
02-793 |
Country |
Poland |
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Platforms (1) |
GPL18460 |
Illumina HiSeq 1500 (Homo sapiens) |
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Samples (8)
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Relations |
BioProject |
PRJNA1201109 |