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Series GSE29251 Query DataSets for GSE29251
Status Public on Jun 01, 2011
Title Genome-wide analysis distinguishes hyperglycemia regulated epigenetic signatures of primary vascular cells (ChIP-seq)
Organism Homo sapiens
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Methylation profiling by high throughput sequencing
Summary We report that hyperglycemia-mediated induction of genes and pathways associated to endothelial dysfunction occur through modulation of acetylated H3K9/K14 inversely correlated with methyl-CpG content.
Overall design Examination of H3K9/K14 histone acetylation and DNA methylation in hyperglycemic conditions.
Contributor(s) Pirola L, Balcerczyk A, Tothill R, Haviv I, Kaspi A, Lunke S, Karagiannis T, Tonna S, Kowalczyk A, Beresford-Smith B, Zieman M, Kelong M, Hongyu Z, Jinfeng S, Zhu J, El-Osta A
Citation(s) 21890681
Submission date May 12, 2011
Last update date May 15, 2019
Contact name Assam El-Osta
Organization name Baker Heart and Diabetes Institute
Lab Human Epigenetics
Street address 75 Commercial Road
City Melbourne
ZIP/Postal code 3004
Country Australia
Platforms (1)
GPL9052 Illumina Genome Analyzer (Homo sapiens)
Samples (13)
GSM723171 HAEC-LG-H3Ac-R1
GSM723172 HAEC-LG-H3Ac-R2
GSM723173 HAEC-LG-H3Ac-R3
SRA SRP006775
BioProject PRJNA139967

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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE29251_H3K914Ac_HGvLG_DN_peaks.bed.gz 44.1 Kb (ftp)(http) BED
GSE29251_H3K914Ac_HGvLG_UP_peaks.bed.gz 105.0 Kb (ftp)(http) BED
GSE29251_MM_HGvLG_DN_peaks.bed.gz 59.5 Kb (ftp)(http) BED
GSE29251_MM_HGvLG_UP_peaks.bed.gz 79.9 Kb (ftp)(http) BED
GSE29251_RAW.tar 10.9 Gb (http)(custom) TAR (of BAM)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file
Processed data are available on Series record

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