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Status |
Public on Jul 19, 2011 |
Title |
Gene expression profiling in the leukemic stem cell-enriched CD34+ fraction identifies target genes that predict prognosis in normal karyotype AML |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
Mononuclear cells from AML patients (n=46) were sorted into CD34+ and CD34- subfractions and genome-wide expression analysis was performed using Illumina BeadChip Arrays (HT12 v3). Of 2 AML samples only the CD34+ fraction could be analyzed. AML CD34+ and CD34- gene expression was compared to a large group of normal CD34+ bone marrow cells (n=31).
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Overall design |
Mononuclear cells from AML patients (n=46) were sorted into CD34+ (46) and CD34- (44) subfractions and genome-wide expression analysis was performed using Illumina BeadChip Arrays (HT12 v3). AML CD34+ and CD34- gene expression was compared to a large group of normal CD34+ bone marrow cells (n=31).
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Contributor(s) |
de Jonge HJ, Woolthuis CM, Vos AZ, Mulder A, van den Berg E, Kluin PM, van der Weide K, de Bont ES, Huls G, Vellenga E, Schuringa JJ |
Citation(s) |
21760593, 25287709 |
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Submission date |
Jun 16, 2011 |
Last update date |
Aug 16, 2018 |
Contact name |
JJ Schuringa |
E-mail(s) |
j.j.schuringa@umcg.nl
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Organization name |
UMCG
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Department |
Experimental Hematology
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Street address |
Hanzeplein 1
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City |
Groningen |
ZIP/Postal code |
9700RB |
Country |
Netherlands |
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Platforms (1) |
GPL6947 |
Illumina HumanHT-12 V3.0 expression beadchip |
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Samples (121)
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Relations |
BioProject |
PRJNA144051 |