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| Status |
Public on Nov 28, 2011 |
| Title |
Gene Array Analyzer (GAA): Alternative usage of gene arrays to study alternative splicing events (MoGene array) |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
The latest version of microarrays released by Affymetrix, the GeneChip Gene 1.0 ST Arrays (gene arrays), are designed in a similar fashion as exon arrays, which enables to identify differentially expressed exons, rather than only the expression level of whole transcripts. Here, we propose an extension, Gene Array Analyzer (GAA), to our previously published Exon Array Analyzer (EAA). GAA enables to analyse gene arrays on exon level and therefore supports to identify alternative splicing with gene arrays. To show the applicability of GAA, we used gene arrays to profile alternative splice events during the development of the heart. Further re-analysis of published gene arrays could show, that some of these splice events reoccur under pathological conditions. The web interface of GAA is user friendly, functional without set up and freely available at http://GAA.mpi-bn.mpg.de.
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| Overall design |
Alternative splicing and gene expression analysis during development of the heart and cardiomyoyte differentiation.
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| Contributor(s) |
Gellert P, Teranishi M, Jenniches K, De Gaspari P, John D, grosse Kreymborg K, Braun T, Uchida S |
| Citation(s) |
22123740 |
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| Submission date |
Jul 06, 2011 |
| Last update date |
Mar 04, 2019 |
| Contact name |
Pascal Gellert |
| E-mail(s) |
pascal.gellert@mpi-bn.mpg.de
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| Phone |
+49 6032 705 1765
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| URL |
http://www.mpi-hlr.de
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| Organization name |
Max Planck Institut for Heart and Lung Research
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| Department |
Cardiac Development and Remodelling
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| Lab |
Braun
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| Street address |
Ludwigstr. 43
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| City |
Bad Nauheim |
| ZIP/Postal code |
61231 |
| Country |
Germany |
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| Platforms (2) |
| GPL6246 |
[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version] |
| GPL10740 |
[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [probe set (exon) version] |
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| Samples (24)
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| GSM754741 |
undifferentiated ES cells, rep 1 [MoGene[exon_level]] |
| GSM754742 |
undifferentiated ES cells, rep 2 [MoGene[exon_level]] |
| GSM754743 |
embryonic bodies, rep 1 [MoGene[exon_level]] |
| GSM754744 |
embryonic bodie, rep 2 [MoGene[exon_level]] |
| GSM754745 |
cardiac bodies, rep 1 [MoGene[exon_level]] |
| GSM754746 |
cardiac bodies, rep 2 [MoGene[exon_level]] |
| GSM754747 |
whole heart, E17.5, rep 1 [MoGene[exon_level]] |
| GSM754748 |
whole heart, E17.5, rep 2 [MoGene[exon_level]] |
| GSM754749 |
whole heart, P1, rep 1 [MoGene[exon_level]] |
| GSM754750 |
whole heart, P1, rep 2 [MoGene[exon_level]] |
| GSM754751 |
undifferentiated ES cells, rep 1 [MoGene[gene_level]] |
| GSM754752 |
undifferentiated ES cells, rep 2 [MoGene[gene_level]] |
| GSM754753 |
embryonic bodies, rep 1 [MoGene[gene_level]] |
| GSM754754 |
embryonic bodie, rep 2 [MoGene[gene_level]] |
| GSM754755 |
cardiac bodies, rep 1 [MoGene[gene_level]] |
| GSM754756 |
cardiac bodies, rep 2 [MoGene[gene_level]] |
| GSM754757 |
whole heart, E17.5, rep 1 [MoGene[gene_level]] |
| GSM754758 |
whole heart, E17.5, rep 2 [MoGene[gene_level]] |
| GSM754759 |
whole heart, P1, rep 1 [MoGene[gene_level]] |
| GSM754760 |
whole heart, P1, rep 2 [MoGene[gene_level]] |
| GSM822325 |
whole heart, adult, rep 1 [MoGene[exon_level]] |
| GSM822326 |
whole heart, adult, rep 2 [MoGene[exon_level]] |
| GSM822327 |
whole heart, adult, rep 1[MoGene[gene_level]] |
| GSM822328 |
whole heart, adult, rep 2[MoGene[gene_level]] |
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| This SubSeries is part of SuperSeries: |
| GSE33183 |
Gene Array Analyzer (GAA): Alternative usage of gene arrays to study alternative splicing events |
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| Relations |
| BioProject |
PRJNA155493 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE30429_RAW.tar |
93.6 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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