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| Status |
Public on Jul 26, 2012 |
| Title |
Expression data from skin biopsy samples from patients with moderate-to-severe psoriasis |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
A gene expression profiling sub-study was conducted in which skin biopsy samples were collected from 85 patients with moderate-to-severe psoriasis who were participating in ACCEPT, an IRB-approved Phase 3, multicenter, randomized trial. This analysis identified 4,175 probe-sets as being significantly modulated in psoriasis lesions (LS) compared with matched biopsies of non-lesional (NL) skin.
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| |
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| Overall design |
Skin biopsy samples (n=170) were collected at baseline for RNA extraction and microarray analysis from 85 patients with moderate-to-severe psoriasis without receiving active psoriasis therapy. The sample title is concatenated as <sample collection site ID>_<subject ID>_<skin type>.
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| |
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| Contributor(s) |
Suárez-Fariñas M, Li K, Fuentes-Duculan J, Hayden K, Brodmerkel C, Krueger JG |
| Citation(s) |
22763790, 27667537 |
| |
| Submission date |
Jul 27, 2011 |
| Last update date |
Mar 25, 2019 |
| Contact name |
K Li |
| E-mail(s) |
kli@its.jnj.com
|
| Organization name |
Janssen R&D
|
| Street address |
1400 McKean Road
|
| City |
Spring House |
| State/province |
PA |
| ZIP/Postal code |
19477 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
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| Samples (170)
|
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| Relations |
| BioProject |
PRJNA146177 |
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