|
| Status |
Public on Jan 01, 2012 |
| Title |
Role of microRNAs in Neural Stem Cell-supported Endothelial Morphogenesis |
| Platform organism |
synthetic construct |
| Sample organism |
Mus musculus |
| Experiment type |
Non-coding RNA profiling by array
|
| Summary |
We checked whether the inhibition of the FGF, VEGF, and TGF signaling pathways would influence the miRNA profile in ECs, co-cultured with NSPCs.
|
| |
|
| Overall design |
EC/NSPC co-cultures were incubated with FGF/VEGF receptor inhibitor PD 173074 (1μM in DMSO), and the TGF-β receptor inhibitor SB431542 (10μM in DMSO, Millipore)
|
| |
|
| Contributor(s) |
Roitbak T, Bragina O, Padilla JL, Pickett GG |
| Citation(s) |
22071092 |
| |
| Submission date |
Sep 23, 2011 |
| Last update date |
May 02, 2017 |
| Contact name |
Tamara Roitbak |
| E-mail(s) |
troitbak@salud.unm.edu, ggpickett@salud.unm.edu
|
| Phone |
505 272-3401
|
| Fax |
505 272-6091
|
| Organization name |
UNM
|
| Department |
Neurosurgery
|
| Street address |
2212 Lomas NE
|
| City |
Albuquerque |
| State/province |
NM |
| ZIP/Postal code |
87131 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL14613 |
[miRNA-2] Affymetrix Multispecies miRNA-2 Array |
|
| Samples (6)
|
| GSM801091 |
ECs from EC/NSPC co-culture, incubated with PD 173074 1 |
| GSM801092 |
ECs from EC/NSPC co-culture, incubated with PD 173074 2 |
| GSM801093 |
ECs from EC/NSPC co-culture incubated with SB431542 1 |
| GSM801094 |
ECs from EC/NSPC co-culture incubated with SB431542 2 |
| GSM801095 |
ECs from EC/NSPC co-culture incubated with DMSO (control) 1 |
| GSM801096 |
ECs from EC/NSPC co-culture incubated with DMSO (control) 2 |
|
| Relations |
| BioProject |
PRJNA147235 |
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