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Series GSE35418 Query DataSets for GSE35418
Status Public on Jan 31, 2012
Title Genome features of “Dark-fly”, a Drosophila line reared long-term in a dark environment
Organism Drosophila melanogaster
Experiment type Genome variation profiling by array
Summary To address the molecular mechanisms underlying environmental adaptation, we studied a Drosophila melanogaster line, termed Dark-fly, which has been maintained in constant dark conditions for 57 years (1400 generations).The structural gene copy number changes between the dark fly and its control were assessed by aCGH array. The comparison showed that hundreds of genes in the dark fly bear duplications or deletions relative to the control line.
Overall design The copy number increase and decrease in the dark flies were determined by two-channel array hybridization with the control line. In addition to biological replicates, a Cy5-Cy3 dye swap was performed.Self-hybridization was also conducted to serve as a quality control.
Contributor(s) Zhou J, Fuse N
Citation(s) 22432011
Submission date Jan 30, 2012
Last update date Aug 14, 2018
Contact name Jun Zhou
Phone 617-496-5540
Fax 617-496-5854
Organization name Harvard University
Department Organismic and Evolutionary Biology
Street address 16 Divinity Ave. Rm2112
City Cambridge
State/province MA
ZIP/Postal code 02138
Country USA
Platforms (1)
GPL6056 HartlLab Drosophilamelanogaster PCRproducts 22k
Samples (8)
GSM867877 A282
GSM867878 A283
GSM867879 A284
BioProject PRJNA152577

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE35418_RAW.tar 16.9 Mb (http)(custom) TAR (of GPR)
Processed data included within Sample table

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