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Series GSE35939 Query DataSets for GSE35939
Status Public on Feb 01, 2015
Title Purified touch receptor neurons: expanded polyGlutamine versus control
Organism Caenorhabditis elegans
Experiment type Expression profiling by array
Summary Transcriptional profiling of C.elegans purified touch receptor neuron precursors, comparing cells expressing mutant Huntingtin N-terminal fragment to normal Huntingtin N-terminal fragment, both fused to GFP under mec-3 promoter. As a control the same experiment has been done with comparing cell expressing normal Huntingtin to GFP only. Goal was to determine the specific effect of expanded polyglutamines on gene expression in purified cell population.
Overall design Three-condition experiment: mutant Huntingtin (128Q) versus normal Huntingtin (19Q), and normal Huntingtin versus GFP only, 3 biological replicates of each. Cells were purified based on GFP fluorescence using a cell sorter.
Contributor(s) Neri C, Tourette C
Citation(s) 24960609
Submission date Feb 20, 2012
Last update date Aug 24, 2015
Contact name Christian Neri
Phone +33 1 44 27 60 45
Organization name Sorbonne Université, CNRS, INSERM
Department CNRS UMR 8256, Inserm ERL U1164
Lab Brain-C lab
Street address 9 quai St Bernard
City Paris
ZIP/Postal code 75005
Country France
Platforms (1)
GPL2875 Agilent-012795 C. elegans Oligo Microarray G2518A Option 002 (Feature Number version)
Samples (6)
GSM877798 Mutant Huntingtin sorted cells replicate-1
GSM877799 Mutant Huntingtin sorted cells replicate-2
GSM877800 Mutant Huntingtin sorted cells replicate-3
BioProject PRJNA152085

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SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE35939_RAW.tar 14.7 Mb (http)(custom) TAR (of GPR)
Processed data included within Sample table

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