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Series GSE44738 Query DataSets for GSE44738
Status Public on Sep 01, 2013
Title Methylated DNA immunoprecipitation coupled with NimbleGen's array to identify methylated genes in pancreatic ductal adenocarcinoma
Organism Homo sapiens
Experiment type Methylation profiling by genome tiling array
Summary Pancreatic ductal adenocarcinoma (PDAC) is a highly invasive cancer with a poor prognosis. Using methylated DNA immunoprecipitation (MeDIP)-chip analysis, we found that 161 genes that were specifically hypermethylated in PANC-1 cells. Among them, miR-615-5p was hypermethylated in its putative promoter region, which silenced its expression in PDAC cell lines.
Overall design Comparison between PANC-1 cell lines and normal pancreas tissue
Contributor(s) Gao W, Miao Y
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Submission date Feb 28, 2013
Last update date Sep 03, 2013
Contact name wentao gao
Phone 13584026196
Fax 86-25-83781992
Organization name the first affiliated hospital with nanjing medical university
Department Department of General Surgery
Street address 300 Guangzhou Road
City Nanjing
ZIP/Postal code 210029
Country China
Platforms (1)
GPL16062 NimbleGen Human DNA Methylation 385K Promoter Plus CpG Island Array [2006-11-02_HG18_CpG_Promo]
Samples (2)
GSM1089822 Normal pancreas tissue - MeDIP
GSM1089823 PANC-1 - MeDIP
BioProject PRJNA191147

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE44738_MeDIP-chip_Protocol.pdf.gz 168.2 Kb (ftp)(http) PDF
GSE44738_MeDIP_protocol.pdf.gz 213.6 Kb (ftp)(http) PDF
GSE44738_RAW.tar 72.3 Mb (http)(custom) TAR (of GFF, PAIR)
Processed data included within Sample table
Processed data provided as supplementary file

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