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Series GSE50176 Query DataSets for GSE50176
Status Public on Oct 01, 2014
Title Inhalation of rod-like carbon nanotubes causes unconventional asthma
Organism Mus musculus
Experiment type Expression profiling by array
Summary Exposure to rod-shaped carbon nanotubes reveals novel innate immunity mediated asthma-like inflammation in mice. Inhalation of rCNT elicited a drastic infiltration of eosinophils into the lungs but only minor infiltration of neutrophils and lymphocytes. Transcriptomic study revealed remarkable effects of rCNT exposure, affecting almost exclusively pathways essential for innate immunity.
Overall design Mice were exposed to rCNT or tCNT for 4 h and sacrificed immediately or 24 h after the exposure. The total RNA was extracted from lung samples, hybridized to Agilent microarray and analyzed with BioConductor package Limma. Untreated mice were used as control.
Contributor(s) Rydman E, Ilves M, Koivisto J, Kinaret P, Fortino V, Savinko T, Lehto M, Pulkkinen V, Vippola M, Hämeri K, Matikainen S, Wolff H, Savolainen K, Greco D, Alenius H
Citation(s) 25318534
Submission date Aug 25, 2013
Last update date Jun 17, 2019
Contact name Dario Greco
Organization name Tampere University
Department Faculty of Medicine and Health Technology
Lab Finnish Hub for Development and Validation of Integrated Approaches (FHAIVE)
Street address Arvo ylpön Katu 34
City Tampere
ZIP/Postal code 33520
Country Finland
Platforms (1)
GPL13912 Agilent-028005 SurePrint G3 Mouse GE 8x60K Microarray (Feature Number version)
Samples (18)
GSM1215115 rCNT 4h.0h [A23 5-5+2]
GSM1215116 tCNT4h.0h [A25 2-1+7]
GSM1215117 UT [A25 1-4+6]
BioProject PRJNA216968

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE50176_Pool1+Pool2_US23502401_252800516533_S01_GE2_1100_Jul11_1_1.txt.gz 6.0 Mb (ftp)(http) TXT
GSE50176_Pool11+Pool12_US23502401_252800516533_S01_GE2_1100_Jul11_2_2.txt.gz 6.1 Mb (ftp)(http) TXT
GSE50176_Pool13+Pool14_US23502401_252800516533_S01_GE2_1100_Jul11_2_3.txt.gz 6.0 Mb (ftp)(http) TXT
GSE50176_Pool15+Pool16_US23502401_252800516533_S01_GE2_1100_Jul11_2_4.txt.gz 6.1 Mb (ftp)(http) TXT
GSE50176_Pool17+Pool18_US23502401_252800516534_S01_GE2_1100_Jul11_1_1.txt.gz 6.1 Mb (ftp)(http) TXT
GSE50176_Pool19+Pool20_US23502401_252800516534_S01_GE2_1100_Jul11_1_2.txt.gz 6.1 Mb (ftp)(http) TXT
GSE50176_Pool21+Pool22_US23502401_252800516534_S01_GE2_1100_Jul11_1_3.txt.gz 6.1 Mb (ftp)(http) TXT
GSE50176_Pool23+Pool24_US23502401_252800516534_S01_GE2_1100_Jul11_1_4.txt.gz 6.1 Mb (ftp)(http) TXT
GSE50176_Pool3+Pool4_US23502401_252800516533_S01_GE2_1100_Jul11_1_2.txt.gz 6.1 Mb (ftp)(http) TXT
GSE50176_Pool5+Pool6_US23502401_252800516533_S01_GE2_1100_Jul11_1_3.txt.gz 6.1 Mb (ftp)(http) TXT
GSE50176_Pool7+Pool8_US23502401_252800516533_S01_GE2_1100_Jul11_1_4.txt.gz 6.1 Mb (ftp)(http) TXT
GSE50176_Pool9+Pool10_US23502401_252800516533_S01_GE2_1100_Jul11_2_1.txt.gz 6.1 Mb (ftp)(http) TXT
GSE50176_RAW.tar 7.9 Mb (http)(custom) TAR
Processed data included within Sample table

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