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Status |
Public on Mar 17, 2014 |
Title |
Transcriptional comparison of the filamentous fungus Neurospora crassa growing on three major monosaccharides D-glucose, D-xylose and L-arabinose |
Organism |
Neurospora crassa |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
D-glucose, D-xylose and L-arabinose are three major monosaccharides in the plant cell wall. Complete utilization of all three sugars is still a bottleneck for second-generation cellulolytic bioethanol production, especially for L-arabinose. However, little is known about the gene expression profiles during L-arabinose utilization in fungi at genome-wide level and a comparison of the genome-wide fungal response to these three major monosaccharides has not yet been reported. To better understand the microbial response and utilization of L-arabinose for subsequent microbial engineering for co-fermentation all three sugars, we performed transcriptome analysis of N. crassa grown on L-arabinose, compared with that on D-xylose and D-glucose.
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Overall design |
RNA was extracted from cultures of N. carassa in early growth stage growing with D-glucose, L-arabinose or D-xylose as carbon source; duplicate cultures were sampled in some conditions.
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Contributor(s) |
Li J, Tian C |
Citation(s) |
24581151 |
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Submission date |
Sep 23, 2013 |
Last update date |
May 15, 2019 |
Contact name |
Jingen Li |
E-mail(s) |
li_jg@tib.cas.cn
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Phone |
+86-02284861948
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Organization name |
Tianjin institute of industrial biotechnology,Chinses Academy of Sciences
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Street address |
Xiqi Dao 32, Tianjin Airport Economic Area
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City |
Tianjin |
ZIP/Postal code |
300308 |
Country |
China |
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Platforms (1) |
GPL16164 |
Illumina HiSeq 2000 (Neurospora crassa) |
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Samples (5)
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Relations |
BioProject |
PRJNA221152 |
SRA |
SRP030206 |