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Series GSE51625 Query DataSets for GSE51625
Status Public on Oct 29, 2013
Title Expression data from human abdominal, subcutaneous adipose tissue
Organism Homo sapiens
Experiment type Expression profiling by array
Summary FCHL is a common, complex genetic lipid disorder with a largely unknown aetiology. Altered adipose tissue metabolism has been implicated as contributing to FCHL.
We used microarrays to investigate the mRNA profiles of FCHL patients with CHD and non-FCHL patients with CHD in comparison with non-FCHL, non-CHD patients to define a core set of genes that were differentially expressed in FCHL and to provide a reasonable launch-pad for examining the direct contribution of one of this gene set to the development of adipose tissue.
Overall design Adipose tissue was obtained from the same anatomical site - the subcutaneous, upper abdominal region - of white British males, either at coronary artery bypass surgery (designated as: FCHL-CHD (13 individuals, subdivided on TG response to statins into Group 1 (n=4), Group 2 (n=7) and unclassified (n=2)) and non-FCHL-CHD patients (6 individuals)), or at heart valve replacement: non-FCHL, non-CHD subjects (5 individuals; controls).
Contributor(s) Horswell SD, Zindrou D, Naoumova R, Scott J, Shoulders CC
Citation(s) 24103848
Submission date Oct 23, 2013
Last update date Dec 13, 2018
Contact name Carol Shoulders
Organization name QMUL
Department Centre for Endocrinology
Street address Charterhouse Square
City London
ZIP/Postal code EC1M 6BQ
Country United Kingdom
Platforms (6)
GPL91 [HG_U95A] Affymetrix Human Genome U95A Array
GPL92 [HG_U95B] Affymetrix Human Genome U95B Array
GPL93 [HG_U95C] Affymetrix Human Genome U95C Array
Samples (120)
GSM1249555 CHD-NONFCHL patient 1 [GPL91]
GSM1249556 CHD-NONFCHL patient 2 [GPL91]
GSM1249557 FCHL-CHD patient 1 [GPL91]
BioProject PRJNA225013

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Supplementary file Size Download File type/resource
GSE51625_RAW.tar 340.1 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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