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Series GSE52137 Query DataSets for GSE52137
Status Public on Apr 01, 2017
Title Expression data from thymic epithelial cells of 5-6 weeks old C57BL/6J mice.
Organism Mus musculus
Experiment type Expression profiling by array
Summary Defects in thymic epithelial cell development causes autoimmune diseases due to breakdown of central tolerance, including skin inflammation. IKKa may be essential to link central tolerance to skin inflammation.
We used microarrays to examine the global gene expression with or without kinase inactive IKKa, and identified a distinct set of down-regulated genes in the presence of kinase-dead IKKa in thymic epithelial cells.
 
Overall design Thymic epithelial cells were isolated from 5-6 weeks old mice. Total RNAs were extracted, and then subjected to Affymetrix mouse genome 430 2.0 array.
 
Contributor(s) Zhu F, Hu Y, Davis S
Citation(s) 28407484
Submission date Nov 06, 2013
Last update date May 22, 2019
Contact name Sean Davis
E-mail(s) sdavis2@mail.nih.gov
Phone 301-435-2652
Organization name National Cancer Institute
Lab Genetics Branch
Street address 37 Convent Drive, Room 6138
City Bethesda
State/province MD
ZIP/Postal code 20892
Country USA
 
Platforms (1)
GPL1261 [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Samples (6)
GSM1260190 KA1
GSM1260191 KA2
GSM1260192 KA3
Relations
BioProject PRJNA227012

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Supplementary file Size Download File type/resource
GSE52137_RAW.tar 21.0 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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