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| Status |
Public on Nov 13, 2013 |
| Title |
Chip-chip from HepG2 cells with EZH2, SUZ12 and H3K27me3 |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by genome tiling array
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| Summary |
Polycomb group (PcG) proteins including EZH2, SUZ12 and so on, which specifically catalyze trimethylation of histone 3 lysine 27 (H3K27me3), and methylated H3K27 can be recognized by other specific binding proteins to compress chromatin structure, leading to the transcriptional repression of the target genes.
To completely understand the epigenetic profile and molecular network of PcG in HCC, we performed ChIP-on-chip screens with EZH2, SUZ12 and H3K27me3 antibodies in HepG2 cells.
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| Overall design |
Comparison of ChIP-on-chip results from EZH2, SUZ12 and H3K27me3.
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| Contributor(s) |
Xu B, Gao S |
| Citation(s) |
24916103 |
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| Submission date |
Nov 12, 2013 |
| Last update date |
Nov 05, 2014 |
| Contact name |
Shubin Gao |
| E-mail(s) |
shbgao@xmu.edu.cn
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| Phone |
+86-592-218-1535
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| Organization name |
Medical College,Xiamen University
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| Department |
Basic Medical Sciences
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| Street address |
Chengzhi building 110,Xiang'an South Road
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| City |
Xiamen |
| ZIP/Postal code |
361102 |
| Country |
China |
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| Platforms (1) |
| GPL9448 |
NimbleGen Human HG18 RefSeq Promoter 385K tiling array |
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| Samples (3) |
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| Relations |
| BioProject |
PRJNA227365 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE52300_Compare_Result.xlsx.gz |
1.9 Mb |
(ftp)(http) |
XLSX |
| GSE52300_Data_Analysis_Result.xlsx.gz |
3.0 Mb |
(ftp)(http) |
XLSX |
| GSE52300_RAW.tar |
106.9 Mb |
(http)(custom) |
TAR (of GFF, JPG, PAIR) |
| Processed data included within Sample table |
| Processed data provided as supplementary file |
| Processed data are available on Series record |
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