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Status |
Public on Nov 13, 2015 |
Title |
Study of the impact of G9a on DNA methylation in mouse embryonic cells [array] |
Organism |
Mus musculus |
Experiment type |
Methylation profiling by genome tiling array
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Summary |
We explored the role of the lysine-methyltrasferase G9a in the control of DNA methylation during mouse embryogenesis. We provide maps of cytosine methylation by MeDIP and RRBS in G9a-deficient mouse embryos and ES cells, as well as ChIP-Seq profiles for H3K9me2 in embryos and RNA-Seq expression profiles in G9a-deficient embryos.
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Overall design |
We mapped DNA methylation by MeDIP in WT and G9aKO E9.5 embryos. Experiments were performed in triplicates, and MeDIP and Input samples were hybridized to Nimblegen HD2 mm9 promoter deluxe arrays covering 12 kb of all gene promoters.
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Contributor(s) |
Weber M, Guibert S |
Citation(s) |
26576615 |
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Submission date |
Feb 14, 2014 |
Last update date |
Feb 12, 2016 |
Contact name |
Michael Weber |
Organization name |
CNRS
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Department |
UMR7242 Biotechnology and Cell Signalling
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Street address |
300 Bd Sebastien Brant
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City |
Illkirch |
ZIP/Postal code |
67412 |
Country |
France |
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Platforms (1) |
GPL17878 |
NimbleGen Mouse MM9 Deluxe Promoter Array (100718_MM9_Promoter_MeDIP_HX1) |
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Samples (6)
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This SubSeries is part of SuperSeries: |
GSE71500 |
Study of the impact of G9a on DNA methylation in mouse embryonic cells |
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Relations |
BioProject |
PRJNA238337 |