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Series GSE56298 Query DataSets for GSE56298
Status Public on Jul 01, 2014
Title Allele-Specific Methylation Occurs at Genetic Variants Associated with Complex Disease
Organism Homo sapiens
Experiment type Methylation profiling by high throughput sequencing
Summary We use targeted bisulfite PCR and next-generation 454 sequencing of multiple amplicons to analyze the association of cis-regulated allele-specific methylation (ASM) with multiple complex disease-associated variants in a population of 82 individuals. We detect ASM at four variants implicated in complex phenotypes such as ulcerative colitis and AIDS progression disease (rs10491434), Celiac disease (rs2762051), Crohn’s disease, IgA nephropathy and early-onset inflammatory bowel disease (rs713875) and height (rs6569648).
 
Overall design 82 samples analysed
 
Contributor(s) Hutchinson JN
Citation(s) 24911414
Submission date Mar 27, 2014
Last update date May 15, 2019
Contact name John N Hutchinson
Organization name Harvard Chan School of Public Health
Street address 677 Huntington Avenue
City Boston
State/province Massachusetts
ZIP/Postal code 02215
Country USA
 
Platforms (1)
GPL9186 454 GS FLX (Homo sapiens)
Samples (82)
GSM1358490 A01
GSM1358491 A03
GSM1358492 A04
Relations
BioProject PRJNA242865
SRA SRP040663

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE56298_RAW.tar 900.0 Kb (http)(custom) TAR (of TAB)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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