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| Status |
Public on Nov 17, 2014 |
| Title |
Genome wide TFIIB binding during postnatal and pressure-induced cardiac hypertrophy |
| Organism |
Mus musculus |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
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| Summary |
Purpose: To identify the differential TFIIB bindingl patterns during postnatal cardiac growth, pressure-induced cardiac hypertrophy and adult mouse hearts
Methods: Hearts were extracted from 1-2day old C57 mice, from mice subjecetd to Transaortic coarctation or adult mice. The hearts were sent to Active Motif for TFIIB- ChIP-Seq.
Results: In accordance with previosly published data (Sayed D, et. al. JBC, 2013 Jan 25;288(4):2546-58) with genome wide polII and H3K9ac status during cardiac hypertrophy (GSE50637), Denovo TFIIB recruitment was restricted to speclaized genes with cardiac hypertrophy.
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| Overall design |
Hearts were extracted from 1-2day old C57 mice, from mice subjecetd to Transaortic coarctation or adult mice. The hearts were sent to Active Motif for TFIIB- ChIP-Seq.
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| Contributor(s) |
Abdellatif M, Sayed D |
| Citation(s) |
25398966, 26675618 |
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| Submission date |
Apr 15, 2014 |
| Last update date |
Oct 09, 2019 |
| Contact name |
Danish Sayed |
| E-mail(s) |
sayeddh@njms.rutgers.edu
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| Phone |
(973) 972-5243
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| Organization name |
Rutgers-NJMS
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| Department |
CBMM
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| Lab |
MSB G 626
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| Street address |
185 south orange avenue
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| City |
Newark |
| State/province |
NJ |
| ZIP/Postal code |
07103 |
| Country |
USA |
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| Platforms (1) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
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| Samples (4)
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| Relations |
| BioProject |
PRJNA244672 |
| SRA |
SRP041188 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE56813_2176Rutgers_TFIIB_actregs.xlsx.gz |
3.3 Mb |
(ftp)(http) |
XLSX |
| GSE56813_2176Rutgers_TFIIB_genes.xlsx.gz |
3.6 Mb |
(ftp)(http) |
XLSX |
| GSE56813_Data_Explan_CSeq_v14-2013_.pdf.gz |
212.5 Kb |
(ftp)(http) |
PDF |
| GSE56813_RAW.tar |
276.8 Mb |
(http)(custom) |
TAR (of BAR) |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data provided as supplementary file |
| Processed data are available on Series record |
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