NCBI Logo
GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
          Go
Series GSE61509 Query DataSets for GSE61509
Status Public on Jan 31, 2016
Title Expression profiling pooled Drosophila melanogaster heterozygous for deletions on Chromosome 2L
Organism Drosophila melanogaster
Experiment type Expression profiling by high throughput sequencing
Summary We performed mRNA transcriptional profiling on 99 hemizygotic lines (Df/+) from the DrosDel project covering 68% of chromosome 2L, in order to understand how changes in gene copy number affect overall transcriptome.
 
Overall design We performed RNA-Seq analysis on 396 pools of 15-25 adult flies each. Samples include males or females from 99 different genotypes in duplicate. Differential gene expression was analyzed separately for each sex, by comparing each genotype with the remaining 98.
 
Contributor(s) Lee H, Russell S, Oliver B
Citation(s) 27599372, 29242386
Hangnoh Lee, Dong-Yeon Cho, Cale Whitworth, Robert Eisman, Melissa Phelps, John Roote, Thomas Kaufman, Kevin Cook, Steven Russell, Teresa M Przytycka, Brian Oliver. Genome-wide expression profiling Drosophila melanogaster deficiency heterozygotes reveals diverse genomic responses. bioRxiv doi: http://dx.doi.org/10.1101/032920
Dong-Yeon Cho, Hangnoh Lee, Damian Wojtowicz, Steven Russell, Brian Oliver, Teresa M Przytycka. Interplay between copy number, dosage compensation and expression noise in Drosophila. bioRxiv doi: https://doi.org/10.1101/041038
Submission date Sep 17, 2014
Last update date Aug 13, 2019
Contact name Brian Oliver
E-mail(s) briano@nih.gov
Phone 301-204-9463
Organization name NIDDK, NIH
Department LBG
Lab Developmental Genomics
Street address 50 South Drive
City Bethesda
State/province MD
ZIP/Postal code 20892
Country USA
 
Platforms (1)
GPL13304 Illumina HiSeq 2000 (Drosophila melanogaster)
Samples (396)
GSM1506809 Df(2L)ED3/+_female_rep1
GSM1506810 Df(2L)ED3/+_female_rep2
GSM1506811 Df(2L)ED3/+_male_rep1
Relations
BioProject PRJNA261333
SRA SRP047246

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE61509_RAW.tar 200.2 Mb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap