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| Status |
Public on Oct 02, 2014 |
| Title |
Expression of miRNAs in human colorectal carcinoma cells upon autophagy induction |
| Platform organisms |
Homo sapiens; Human alphaherpesvirus 1; Human alphaherpesvirus 2; Cytomegalovirus; Lymphocryptovirus; Rhadinovirus; JC polyomavirus; Human immunodeficiency virus 1; Merkel cell polyomavirus; Betapolyomavirus hominis; Betapolyomavirus macacae |
| Sample organism |
Homo sapiens |
| Experiment type |
Non-coding RNA profiling by array
|
| Summary |
The expression profile of miRNAs during the response of human colon cancer cells (HT29s) to 5-FU treatment and nutrient starvation was examined using miRNA microarray analysis. Combining with the following real time PCR and bioinformatics analysis, the physiological importance of the miRNA-autophagy interconnection is far more likely to be elucidated.
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| Overall design |
In the study presented here, autophagy induction was confirmed in both 5-FU-treated HT29 cells and nutrient-starved HT29 cells. These cells were used to acquire expression profiles of all human miRNAs annotated in miRBase 18.0
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| Contributor(s) |
Hou N, Huang C |
| Citation(s) |
25526515 |
| |
| Submission date |
Oct 01, 2014 |
| Last update date |
Jan 03, 2015 |
| Contact name |
Ni Hou |
| E-mail(s) |
houni.0627@hotmail.com
|
| Organization name |
Xi'an Jiaotong University
|
| Department |
Department of Genetics and Molecular Biology
|
| Street address |
76 Western Yanta Road
|
| City |
Xi'an |
| State/province |
Shaanxi Province |
| ZIP/Postal code |
710061 |
| Country |
China |
| |
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| Platforms (1) |
| GPL19128 |
Exiqon miRCURY LNA microRNA array; 7th generation - hsa, mmu & rno (miRBase 18.0) |
|
| Samples (4)
|
| GSM1517533 |
HT29 cell treated by control for nutrient starvation |
| GSM1517534 |
HT29 cell treated by nutrient starvation |
| GSM1517535 |
HT29 cell treated by control for 5-FU treatment |
|
| Relations |
| BioProject |
PRJNA262725 |
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