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Series GSE64123 Query DataSets for GSE64123
Status Public on Jun 01, 2015
Title Human embryonic stem cell based neuro-developmental toxicity assay: response to valproic acid and carbamazepine exposure
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Here we studied the effects of anticonvulsant drug exposure in a human embryonic stem cell (hESC) based neuro- developmental toxicity test (hESTn). During neural differentiation the cells were exposed, for either 1 or 7 days, to non-cytotoxic concentration ranges of valproic acid (VPA) or carbamazepine (CBZ), anti-epileptic drugs known to cause neurodevelopmental toxicity.
 
Overall design 93 samples (multiple time points, multiple exposures, multiple concentrations, multiple replicates)
 
Contributor(s) Pennings J
Citation(s) 25979313
Submission date Dec 12, 2014
Last update date Jun 02, 2015
Contact name Jeroen Pennings
E-mail(s) Jeroen.Pennings@rivm.nl
Phone +31 88 689 2214
Organization name Natl. Inst. Public Health & Environment
Street address A. van Leeuwenhoeklaan 9
City Bilthoven
ZIP/Postal code 3721MA
Country Netherlands
 
Platforms (1)
GPL15798 Affymetrix HT HG-U133+ PM Array Plate [CDF: HTHGU133PlusPM_Hs_ENTREZG_v14]
Samples (93)
GSM1564835 0 days, unexposed, nr1
GSM1564836 0 days, unexposed, nr2
GSM1564837 0 days, unexposed, nr3
Relations
BioProject PRJNA270221

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE64123_RAW.tar 209.0 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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