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| Status |
Public on Jan 22, 2016 |
| Title |
Long-term consequences of chronic fluoxetine exposure on the expression of myelination-related genes in the rat hippocampus |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
To more concretely elucidate the long-term effects of chronic SSRI exposure during adulthood, the long-term consequences of chronic fluoxetine (12 mg/kg) versus vehicle treatment during adulthood (postnatal day (PND) 67-88) on gene expression in the hippocampus were investigated. The study showed that adult chronic fluoxetine exposure causes on the long-term changes in the expression of genes related to, amongst others, myelination
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| |
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| Overall design |
Comparison of gene expression in hippocampus tissue of fluoxetine and methylcellulose-exposed rats (postnatal day 128). 2 rats pooled per sample, 2 samples per treatment group
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| Contributor(s) |
Zhou JH |
| Citation(s) |
26393488 |
| |
| Submission date |
Mar 24, 2015 |
| Last update date |
Jun 14, 2022 |
| Contact name |
Jo Huiqing Zhou |
| E-mail(s) |
jo.zhou@radboudumc.nl
|
| Organization name |
Radboud University
|
| Street address |
Geert Grooteplein 26/28
|
| City |
Nijmegen |
| ZIP/Postal code |
6525GA |
| Country |
Netherlands |
| |
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| Platforms (1) |
| GPL10669 |
Illumina Genome Analyzer IIx (Rattus norvegicus) |
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| Samples (4)
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| Relations |
| BioProject |
PRJNA279259 |
| SRA |
SRP056481 |
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