GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
Series GSE67457 Query DataSets for GSE67457
Status Public on Apr 01, 2015
Title Expression data from prostate cancer cell lines LNCap (androgen dependent) and DU145 (androgen independent), transfected with Pin1 or control siRNA
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Pin1 inhibiton exerts anti-oncogenic effects on LNCaP and DU145 cells despite the gene regulation patterns by Pin1 were different in both cells.
We investigated how Pin1 modulates the gene expressions in the androgen-dependent as well as the androgen-independent prostate cancer cell lines
Overall design For the knockdown of human Pin1, the siRNAs against Pin1 (Pin1 shRNA-1: 5’-CGGCAACAGCAGCAGUGGUGGCAAA-3’ and Pin1 shRNA-2: 5’-GCCCUGGAGCUGAUCAACGGCUACA-3’) and control siRNA were purchased from Invitrogen (Stealth/siRNA duplex oligoribonucleotides)
Contributor(s) Kushiyama A, Kanaoka R, Asano T
Citation(s) 26039047
Submission date Mar 31, 2015
Last update date Jul 26, 2018
Contact name Akifumi Kushiyama
Phone +81-3-3639-5501
Organization name The Institute for Adult Diseases, Asahi Life Foundation
Street address 2-2-6, Nihonbashi Bakurocho, Chuo-ku
City Tokyo
ZIP/Postal code 103-0002
Country Japan
Platforms (1)
GPL6244 [HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version]
Samples (6)
GSM1647378 LNCaP, control siRNA
GSM1647379 LNCaP, Pin1 siRNA-1
GSM1647380 LNCaP, Pin1 siRNA-2
BioProject PRJNA279982

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE67457_MatrixData_Pin1.txt.gz 1.1 Mb (ftp)(http) TXT
GSE67457_RAW.tar 26.8 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table
Processed data are available on Series record

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap