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| Status |
Public on Jun 27, 2015 |
| Title |
Transcriptional programs that regulate brain cortical development |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Dynamic changes of histone epigenetic modifications and chromatin structure represent an universal mechanism by which cells adapt their transcriptional response to rapidly changing environmental conditions. During neuronal development, extensive chromatin remodelling takes place allowing the transition of pluripotent cells into differentiated neurons. Here we investigate the transcriptional programs that are differentially regulated during cortical development in vivo.
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| Overall design |
Gene expression analysis was performed in the mouse embryonic cortex at three developmental stages: E12.5, E15.5 and E18.5 using total RNA obtained from four embryos for each time point.
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| Contributor(s) |
Nitarska J, Mitter R, Riccio A |
| Citation(s) |
27806305 |
| |
| Submission date |
Jun 25, 2015 |
| Last update date |
Jul 15, 2019 |
| Contact name |
Justyna Nitarska |
| Organization name |
University College London
|
| Department |
MRC Laboratory for Molecular Cell Biology
|
| Street address |
Gower Street
|
| City |
London |
| ZIP/Postal code |
WC1E6BT |
| Country |
United Kingdom |
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| Platforms (1) |
| GPL6887 |
Illumina MouseWG-6 v2.0 expression beadchip |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA288281 |
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