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Status |
Public on Nov 26, 2015 |
Title |
Acute loss of TET function results in aggressive myeloid cancer in mice [WGBS] |
Organism |
Mus musculus |
Experiment type |
Methylation profiling by high throughput sequencing
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Summary |
To evaluate the DNA methylation in LSK cells from the bone marrow of wildtype or Tet2/3 DKO mice.
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Overall design |
In order to address the impact of the loss of Tet2/3 proteins in DNA methylation in LSK cells, we compared by WGBS the methylome of wild and, Tet2/3 DKO LSK cells in bone marrow.
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Contributor(s) |
An J, Gonzalez Avalos E, Chavez L, Ko M, Rao A |
Citation missing |
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Submission date |
Sep 02, 2015 |
Last update date |
May 15, 2019 |
Contact name |
Anjana Rao |
E-mail(s) |
arao@lji.org
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Phone |
8587526500
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Organization name |
La Jolla institute
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Department |
Signaling and Gene Epression
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Street address |
9420 Athena Circle
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City |
La Jolla |
State/province |
CA |
ZIP/Postal code |
92037 |
Country |
USA |
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Platforms (1) |
GPL11002 |
Illumina Genome Analyzer IIx (Mus musculus) |
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Samples (6)
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This SubSeries is part of SuperSeries: |
GSE72630 |
Acute loss of TET function results in aggressive myeloid cancer in mice |
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Relations |
BioProject |
PRJNA294516 |
SRA |
SRP063093 |