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Series GSE7331 Query DataSets for GSE7331
Status Public on Oct 11, 2007
Title CGH result of Neisseria meningitidis ST-7 isolates
Organism Neisseria meningitidis
Experiment type Genome variation profiling by array
Summary Neisseria meningitidis is a major cause of bacterial meningitis and septicemia worldwide. Seven new serogroup C meningococci were isolated from two provinces of China in January, 2006. Their PorA VR types were P1.20, 9. Multilocus sequence typing results indicated that they all belonged to ST-7. It is a new serogroup C N. meningitidis sequence type clone identified in China. Here we also present the results of a genomic comparison of these isolates with other 15 N. meningitidis serogroup A and B isolates, which belonged to ST-7, based on comparative genomic hybridization analysis. The data described here would be helpful to monitor the spread of this new serogroup C meningococci sequence type clone in China and worldwide.
Keywords: comparative genomic hybridization
Overall design To compare the genome compositions of these menC ST-7 isolates with those of menC ST-4821 isolates, menA ST-7 isolates and menB ST-7 isolates, we performed comparative genomic hybridization (CGH) analysis among 17 N. meningitidis isolates (including two newly identified menC ST-7 isolates) using an updated version of the whole-genome microarray of N. meningitidis serogroup C isolate 053442 .
Contributor(s) Peng J, Zhang X, Jin Q
Citation(s) 17852942
Submission date Mar 20, 2007
Last update date Mar 16, 2012
Contact name Junping Peng
Organization name Chinese center for disease control and prevention
Lab State key lab for molecular virology and genetic engineering
Street address No 6, Rongjing Eastern Street, BDA
City Beijing
ZIP/Postal code 100176
Country China
Platforms (1)
GPL5011 Neisseria meningitidis 053442 2.5K
Samples (48)
GSM175739 Neisseria meningitidis isolate 510603-1
GSM175740 Neisseria meningitidis isolate 510603-2
GSM175741 Neisseria meningitidis isolate 510603-3
BioProject PRJNA98053

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