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| Status |
Public on Dec 15, 2016 |
| Title |
Expression data from MCF-7 breast cancer cells treated with CNTs, ginsenosides (Rb1 and Rg1) and conjugates (Rb-CNTs and Rg-CNTs) |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
To investigate the effects of ginsenosides-CNTs conjugtaes on total expression profile of MCF-7 breast cancer cells, we conjugated ginsenoides Rb1 and Rg1 with multi-walled carbon nanotubes in a 5:1 ratio.
Objectives for this study included the identification of genes that were up or down-regulated at the transcriptional level in MCF-7 cells treated with ginsenoside-CNTs conjugates and compare it to the ginsenosides alone (Rb1 and Rg1)
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| Overall design |
MCF-7 breast cancer cells were incubated with CNTs (8 ug/ml), Rb1 (2 ug/ml), Rg1 (2 ug/ml), Rb-CNTs (10 ug/ml) and Rg-CNTs (10 ug/ml) for 24 hours and selected for RNA extraction and hybridization on Affymetrix microarrays.
type: cell death responses
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| |
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| Contributor(s) |
Khodakovskaya M |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Dec 01, 2015 |
| Last update date |
Aug 23, 2018 |
| Contact name |
Mariya Khodakovskaya |
| E-mail(s) |
m_khod@yahoo.com
|
| Organization name |
University of Arkansas at Little Rock
|
| Department |
Biology
|
| Street address |
2801 S. University Avenue
|
| City |
Little Rock |
| State/province |
AR |
| ZIP/Postal code |
72204 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL15207 |
[PrimeView] Affymetrix Human Gene Expression Array |
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| Samples (18)
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| Relations |
| BioProject |
PRJNA304617 |
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