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Series GSE75890 Query DataSets for GSE75890
Status Public on Mar 08, 2016
Title Distinct molecular signatures of mild extrinsic and intrinsic atopic dermatitis
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Atopic dermatitis (AD) is a common inflammatory skin disease with underlying defects in epidermal function and immune responses. The goal of this study was to investigate differences in gene expression in lesional skin from patients with mild extrinsic or intrinsic AD compared to skin from healthy controls and from lesional psoriasis skin. The aim was to identify differentially expressed genes involved in skin barrier formation and inflammation, and to compare our results with those reported for patients with moderate and severe AD.
Overall design A total of 31 samples were analyzed: 8 healthy skin, 9 psoriatic plaques, 4 extrinsic AD lesional skin, 10 intrinsic AD lesional skin.
Contributor(s) Martell BC, Litman T
Citation(s) 26841714
Submission date Dec 10, 2015
Last update date Dec 11, 2017
Contact name Thomas Litman
Phone 4541851753
Organization name University of Copenhagen
Department ISIM
Street address Blegdamsvej 3C
City Copenhagen N
State/province Outside the US or Canada
ZIP/Postal code 2200
Country Denmark
Platforms (1)
GPL17692 [HuGene-2_1-st] Affymetrix Human Gene 2.1 ST Array [transcript (gene) version]
Samples (31)
GSM1969475 Pso #1
GSM1969476 Pso #2
GSM1969477 Pso #4
BioProject PRJNA305616

Download family Format
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE75890_RAW.tar 144.9 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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