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| Status |
Public on Jan 01, 2017 |
| Title |
Tissue-specific signatures in the transcriptional response to Anaplasma phagocytophilum infection of Ixodes scapularis and Ixodes ricinus tick cell lines |
| Organism |
Ixodes ricinus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
We report differential gene expression with tissue-specific signatures in tick cell lines infected with Anaplasma phagocytophilum - transcriptional response to infection of I. scapularis ISE6 cells resembled that of tick hemocytes while the response in I. ricinus IRE/CTVM20 cells resembles that of tick midguts.
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| Overall design |
Comparison of differential gene expression in infected tick cell lines (Ixodes scapularis [ISE6] and Ixodes ricinus [IRE/CTVM20]) at 7 days post-infection. Differential gene expression determined through comparison with mock-treated (uninfected) cells. This series contains only Ixodes ricinus data.
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| Contributor(s) |
de la Fuente J, Ellis RJ |
| Citation(s) |
28202075 |
| |
| Submission date |
Jan 15, 2016 |
| Last update date |
May 15, 2019 |
| Contact name |
Richard Ellis |
| Organization name |
Animal and Plant Health Agency
|
| Street address |
APHA Weybridge
|
| City |
Addlestone |
| ZIP/Postal code |
KT15 3NB |
| Country |
United Kingdom |
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| Platforms (1) |
| GPL21340 |
Illumina Genome Analyzer IIx (Ixodes ricinus) |
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| Samples (4)
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| Relations |
| BioProject |
PRJNA308910 |
| SRA |
SRP068499 |
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