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Series GSE79698 Query DataSets for GSE79698
Status Public on Jan 01, 2017
Title The effect of niclosamide on the growth and progression of endometriosis in an experimental mouse model
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary Because niclosamide inhibits growth and progression of endometriotic lesions, we performed RNA-seq in order to identify genes whose expression is regulated by niclosamide in endometriotic lesions. Our results shown that niclosamide modulates several genes related to cell signaling, extracellular matrix, and inflammatory signaling.
Overall design A direct comparison of endometriotic like lesions developed in mice (n=3 per group) treated orally with either vehicle control or 200 mg/kg bw day of niclosamide for 3 weeks.
Contributor(s) Prather GR, Hayashi K, MacLean JA
Citation(s) 27535961
Submission date Mar 29, 2016
Last update date May 15, 2019
Contact name Kanako Hayashi
Organization name Washington State University
Department School of Molecular Biosciences
Street address BLS345, 1770 NE Stadium Way
City Pullman
State/province WA
ZIP/Postal code 99164
Country USA
Platforms (1)
GPL17021 Illumina HiSeq 2500 (Mus musculus)
Samples (6)
GSM2101265 CO_1
GSM2101266 CO_2
GSM2101267 CO_3
BioProject PRJNA316727
SRA SRP072519

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE79698_RAW.tar 16.7 Mb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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