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| Status |
Public on Dec 06, 2016 |
| Title |
The PLETHORA gene regulatory network guides growth and cell differentiation in Arabidopsis roots |
| Organism |
Arabidopsis thaliana |
| Experiment type |
Expression profiling by array
Genome binding/occupancy profiling by high throughput sequencing
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| Summary |
Organ formation in animals and plants relies on precise control of cell state transitions to turn stem cell daughters into fully differentiated cells. In plants, cells cannot rearrange due to shared cell walls. Thus, differentiation progression and the accompanying cell expansion must be tightly coordinated across tissues. PLETHORA (PLT) transcription factor gradients are unique in their ability to guide the progression of cell differentiation at different positions in the growing Arabidopsis root, which contrasts with well-described transcription factor gradients in animals specifying distinct cell fates within an essentially static context. To understand the output of the PLT gradient, we studied the gene set transcriptionally controlled by PLTs. Our work reveals how the PLT gradient can regulate cell state by region-specific induction of cell proliferation genes and repression of differentiation. Moreover, PLT targets include major patterning genes and autoregulatory feedback components, enforcing their role as master regulators of organ development.
This SuperSeries is composed of the SubSeries listed below.
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| Overall design |
Refer to individual Series
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| Web link |
http://www.plantcell.org/content/early/2016/12/05/tpc.16.00656.abstract
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| Citation(s) |
27920338 |
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| Submission date |
Mar 31, 2016 |
| Last update date |
May 15, 2019 |
| Contact name |
Luca Santuari |
| Organization name |
Wageningen University
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| Department |
Plant Sciences Group
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| Lab |
Plant Developmental Biology
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| Street address |
Droevendaalsesteeg 1
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| City |
Wageningen |
| ZIP/Postal code |
6708PB |
| Country |
Netherlands |
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| Platforms (3) |
| GPL10088 |
AB SOLiD System 3.0 (Arabidopsis thaliana) |
| GPL17133 |
[AraGene-1_1-st] Arabidopsis Gene 1.1 ST Array [transcript (gene) version] |
| GPL21674 |
[ATH1-121501] Affymetrix Arabidopsis ATH1 Genome Array [Custom CDF: ATH1121501_At_TAIRG_19.0.0] |
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| Samples (36)
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| GSM2102009 |
4h induction of pPLT2-PLT2-GR in QC cells, biological rep 1 |
| GSM2102010 |
1h induction of pPLT2-PLT2-GR in QC cells, biological rep 1 |
| GSM2102011 |
control, biological rep 1 |
| GSM2102012 |
1h induction of pPLT2-PLT2-GR in QC cells, biological rep 2 |
| GSM2102013 |
control, biological rep 2 |
| GSM2102014 |
4h induction of pPLT2-PLT2-GR in QC cells, biological rep 2 |
| GSM2102015 |
control, biological rep 3 |
| GSM2102016 |
4h induction of pPLT2-PLT2-GR in QC cells, biological rep 3 |
| GSM2102017 |
1h induction of pPLT2-PLT2-GR in QC cells, biological rep 3 |
| GSM2102018 |
mock treatment of 35S-PLT2-GR, biological rep 1 |
| GSM2102019 |
mock treatment of 35S-PLT2-GR, biological rep 2 |
| GSM2102020 |
mock treatment of 35S-PLT2-GR, biological rep 3 |
| GSM2102021 |
induction of 35S-PLT2-GR in whole seedlings, biological rep 1 |
| GSM2102022 |
induction of 35S-PLT2-GR in whole seedlings, biological rep 2 |
| GSM2102023 |
induction of 35S-PLT2-GR in whole seedlings, biological rep 3 |
| GSM2102024 |
mock treatment of 35S-PLT4-GR, biological rep 1 |
| GSM2102025 |
mock treatment of 35S-PLT4-GR, biological rep 2 |
| GSM2102026 |
mock treatment of 35S-PLT4-GR, biological rep 3 |
| GSM2102027 |
mock treatment of 35S-PLT4-GR, biological rep 4 |
| GSM2102028 |
dex induction of 35-PLT1-GR, biological rep 1 |
| GSM2102029 |
dex induction of 35-PLT1-GR, biological rep 2 |
| GSM2102030 |
dex induction of 35-PLT1-GR, biological rep 3 |
| GSM2102031 |
dex induction of 35-PLT3-GR, biological rep 1 |
| GSM2102032 |
dex induction of 35-PLT3-GR, biological rep 2 |
| GSM2102033 |
dex induction of 35-PLT4-GR, biological rep 1 |
| GSM2102034 |
dex induction of 35-PLT4-GR, biological rep 2 |
| GSM2102035 |
dex induction of 35-PLT4-GR, biological rep 3 |
| GSM2102036 |
dex induction of 35-PLT5-GR, biological rep 1 |
| GSM2102037 |
dex induction of 35-PLT5-GR, biological rep 2 |
| GSM2102038 |
dex induction of 35-PLT5-GR, biological rep 3 |
| GSM2102039 |
dex induction of 35-PLT7-GR, biological rep 1 |
| GSM2102040 |
dex induction of 35-PLT7-GR, biological rep 2 |
| GSM2102041 |
dex induction of 35-PLT7-GR, biological rep 3 |
| GSM2102042 |
PLT2_IP1 |
| GSM2102043 |
PLT2_IP2 |
| GSM2102044 |
input DNA |
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| This SuperSeries is composed of the following SubSeries:
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| GSE79751 |
Induction of pPLT2-PLT2-GR in Quiescent Center (QC) cells |
| GSE79752 |
Induction of 35S-PLT2-GR in whole seedlings |
| GSE79753 |
Induction of PLT1, PLT3, PLT4, PLT5 and PLT7 in whole seedlings |
| GSE79754 |
Chromatin immunoprecipitation and sequencing of pPLT2::PLT2-YFP in the root of plt1plt2 double mutant |
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| Relations |
| BioProject |
PRJNA316932 |
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