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Series GSE80505 Query DataSets for GSE80505
Status Public on Apr 22, 2016
Title Genome-wide analysis of differential gene expression after Foxd3 knockdown in colorectal CDCP1+CSCs
Organism Mus musculus
Experiment type Expression profiling by array
Summary Analysis of Foxd3-regulation of self-renewal and quiescence in CDCP1+CSCs at gene expression level. The hypothesis tested in the present study was that the Foxd3 global developmental regulator serves a critical role to support the self-renewal of CDCP1+CSCs as one of few known factors involved in maintaining their quiescence. Results provide important information of the response of colorectal CDCP1+CSCs to depletion of Foxd3, such as genes involved in regulation of cell cycle, cell proliferation, and stem-like properties.
 
Overall design Total RNA obtained from isolated CDCP1+CSCs subjected to 24 hours in vitro Foxd3 shRNA treatment compared to untreated control cells.
 
Contributor(s) Li Q, Gao W
Citation missing Has this study been published? Please login to update or notify GEO.
Submission date Apr 21, 2016
Last update date Jan 16, 2019
Contact name Li Qingquan
E-mail(s) 061101040@fudan.edu.cn
Organization name fudan university
Street address No.138,Yixueyuan Rd.
City Shanghai
ZIP/Postal code 200032
Country China
 
Platforms (1)
GPL6887 Illumina MouseWG-6 v2.0 expression beadchip
Samples (18)
GSM2128855 CDCP1+TICs treated 24h rep1 [FatK1_T1]
GSM2128856 CDCP1+TICs treated 24h rep2 [FatK1_T2]
GSM2128857 CDCP1+TICs treated 24h rep3 [FatK1_T3]
Relations
BioProject PRJNA319149

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE80505_RAW.tar 15.8 Mb (http)(custom) TAR
GSE80505_non_normalized.txt.gz 5.4 Mb (ftp)(http) TXT
Processed data included within Sample table

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