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Series GSE80519 Query DataSets for GSE80519
Status Public on Aug 10, 2016
Title Genomic landscape affected by allelic imbalance in the cancerization filed of normal appearing airway
Organism Homo sapiens
Experiment type Genome variation profiling by SNP array
SNP genotyping by SNP array
Summary Normal appearing airway samples from non-small cell lung (NSCLC) cancer patients were profiled using illumina sequencing arrays. Allelic imbalance was detected in normal-appearing large and small airway samples and affected known lung cancer driver genes.
Overall design Multiple airway samples from 45 patients were analyzed using illumina sequencing arrays in order to comprehensively asses the genomic landscape of airway epithelia adjacent to NSCLC. For each patients there was at least one small airway sample, a tumor samples, as well as germline control sample (blood and/or normal uninvolved lung). In addition to these samples additional samples were analyzed for a subset of patients these included large airway, nasal, and multiple core needle biopsies from the tumor.
Contributor(s) Jakubek Y, Scheet P, Kadara H
Citation(s) 27216194
Submission date Apr 21, 2016
Last update date Aug 10, 2016
Contact name Yasminka Aleksandra Jakubek
Organization name University of Texas MD Anderson Cancer Center
Department Epidemiology
Lab Scheet
Street address 1155 Pressler St
City Houston
State/province TX
ZIP/Postal code 77030
Country USA
Platforms (1)
GPL20333 Illumna HumanOmniExpressExome-8 v1.2
Samples (435)
GSM2129208 patient 001 NSCLC [001_001]
GSM2129209 patient 001 normal lung tissue [001_002]
GSM2129210 patient 001 small adjacent airway [001_003]
BioProject PRJNA319250

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE80519_Matrix_processed_Jakubek.txt.gz 3.5 Gb (ftp)(http) TXT
GSE80519_Matrix_signal_intensities_Jakubek.txt.gz 3.3 Gb (ftp)(http) TXT
GSE80519_RAW.tar 93.8 Mb (http)(custom) TAR
Processed data are available on Series record

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