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Series GSE80678 Query DataSets for GSE80678
Status Public on Aug 10, 2016
Title Gene expression signatures for primary tumor and tumor-derived exosomes
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary To determine the different gene signatures between primary tumor and tumor-derived exosomes, we have employed RNA-sequencing as a discovery platform to identify gene signatures of tumor-derived exosomes, taking the original tumors as a control. We subcutaneously inoculated C57BL/6 mice with Lewis lung carcinoma (LLC). Three weeks later, tumor tissues were cut and tumor-derived exosomes were isolated as described in the "treatment protocol". Then, both exosomal RNA and tumor RNA were extracted and sequenced. From sequencing, we found that exosomal RNAs showed quite different transcript profiles from tumor RNAs.
Overall design Examination of different gene signatures between primary tumor and tumor-derived exosomes. 2 replicates each.
Contributor(s) Cao X, Liu Y
Citation(s) 27505671
Submission date Apr 26, 2016
Last update date May 15, 2019
Contact name Liu Yanfang
Phone 0086-13918386805
Organization name Second Military Medical University
Department Immunology
Street address 800 Xiangyin Road
City Shanghai
ZIP/Postal code 200433
Country China
Platforms (1)
GPL17021 Illumina HiSeq 2500 (Mus musculus)
Samples (4)
GSM2133237 ExoRNA_1
GSM2133238 ExoRNA_2
GSM2133239 Tumor RNA_1
BioProject PRJNA319654
SRA SRP073932

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SOFT formatted family file(s) SOFTHelp
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE80678_RAW.tar 750.0 Kb (http)(custom) TAR (of TXT)
GSE80678_total_processed_data.txt.gz 363.2 Kb (ftp)(http) TXT
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Raw data are available in SRA
Processed data provided as supplementary file
Processed data are available on Series record

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