|
Status |
Public on Jun 21, 2017 |
Title |
Transcriptional Changes in Escherichia coli Upon Treatment with (-)-Roemerine |
Platform organisms |
Escherichia coli O157:H7 str. EDL933; Escherichia coli CFT073; Escherichia coli O157:H7 str. Sakai; Escherichia coli str. K-12 substr. MG1655 |
Sample organism |
Escherichia coli |
Experiment type |
Expression profiling by array
|
Summary |
Transcriptional profiling of Escherichia coli TB1 cells under (-)-Roemerine treatment. The genome reprograming in the bacterial cells at transcription level was analyzed through treatment of the bacteria with plant-derived alkaloid, (-)-Roemerine, to elucidate the response of bacteria to the antibacterial drug.
|
|
|
Overall design |
Two-condition experiment, DMSO vs. DMSO+Roemerine treated cells, at two different time points, 0 vs. 60 min. after treatment. Biological replicates: 7 control replicates (3 samples for 0 min., 4 samples for 60 min.), 6 Roemerine treated replicates (3 samples for 0 min., 3 samples for 60 min)
|
|
|
Contributor(s) |
Sariyar Akbulut B, Ayyildiz D, Arga K |
Citation(s) |
28013396 |
|
Submission date |
Apr 29, 2016 |
Last update date |
Jul 11, 2017 |
Contact name |
Dilara Ayyıldız |
E-mail(s) |
dilarayyildiz@gmail.com
|
Phone |
+39 366 8933431
|
Organization name |
University of Udine
|
Street address |
p.le kolbe, 4
|
City |
Udine |
ZIP/Postal code |
33100 |
Country |
Italy |
|
|
Platforms (1) |
GPL13359 |
Agilent-020097 E. coli Gene Expression Microarray (Probe Name version) |
|
Samples (13)
|
|
Relations |
BioProject |
PRJNA320094 |