|
| Status |
Public on Jun 12, 2017 |
| Title |
Social defeat effect on mice prefrontal cortex |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Behavioral analysis confirmed that the 14-day social defeat sessions resulted in induction of depressive-like states measured in social interaction and light/dark tests. The combined data show that stress-induced depressive states are associated with molecular and structural changes that demyelinate the prefrontal cortex.
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| Overall design |
CSD and HC male mice (6 per group) were tested in the social interaction test and light/dark test to gauge mood. One behavioral test was run per day.
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| Contributor(s) |
Elkahloun AG, Lehmann M |
| Citation(s) |
28418035 |
| |
| Submission date |
Jul 19, 2016 |
| Last update date |
Mar 04, 2019 |
| Contact name |
abdel elkahloun |
| E-mail(s) |
abdel@mail.nih.gov
|
| Organization name |
nih
|
| Street address |
50 south dr
|
| City |
bethesda |
| State/province |
MD |
| ZIP/Postal code |
20892 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL6246 |
[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version] |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA329654 |
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