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| Status |
Public on Mar 30, 2017 |
| Title |
Foxh1 marks the embryonic genome prior to the activation of the mesendoderm gene regulatory program |
| Organism |
Xenopus tropicalis |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
Third-party reanalysis
|
| Summary |
We examined the binding dynamics of the maternal TF Foxh1 over a time course of germ layer development. Foxh1 binding was compared to the onset of zygotic transcription (RNA pol II), binding of the co-repressor Tle, Nodal signaling (Smad2/3) and the zygotic endoderm TF Foxa.
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| Overall design |
ChIP-seq analysis of transcription factors Foxh1 and Foxa, RNA Polymerase II and the co-repressor TLE, during zygotic gene activation and germ layer development. Includes biological replicates and stage-matched input controls. Five Samples from GSE53652 are included in this study. The reanalyzed processed data for these Samples are on the Series record.
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| |
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| Contributor(s) |
Charney RM, Cho KW |
| Citation(s) |
28325473 |
| |
| Submission date |
Aug 06, 2016 |
| Last update date |
May 15, 2019 |
| Contact name |
Rebekah M Charney |
| E-mail(s) |
rcharney@uci.edu
|
| Organization name |
University of California, Irvine
|
| Department |
Developmental and Cell Biology
|
| Lab |
Ken Cho
|
| Street address |
4410 Natural Sciences II
|
| City |
Irvine |
| State/province |
CA |
| ZIP/Postal code |
92697 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL21875 |
Illumina HiSeq 2500 (Xenopus tropicalis) |
|
| Samples (11)
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| Relations |
| Reanalysis of |
GSM1298090 |
| Reanalysis of |
GSM1298091 |
| Reanalysis of |
GSM1298092 |
| Reanalysis of |
GSM1298093 |
| Reanalysis of |
GSM1298094 |
| BioProject |
PRJNA338166 |
| SRA |
SRP081096 |
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