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Series GSE85302 Query DataSets for GSE85302
Status Public on Sep 02, 2016
Title KAT6A determines CD8+ T cell diversity via regulation of co-receptors
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary To identify genes specifically expressed in WT or Kat6a knockout CD8+ T cells, the gene expression profiles of T cell subsets from naïve or LCMV WE infected mice were compared.
 
Overall design Three wildtype and three Kat6a knockout P14 transgenic mice were infected with LCMV WE for 8 days. Two wildtype and two knockout mice were uninfected. CD8+ T cells were harvested from the spleens of all mice. In the infected cohort, the T cells were further subsetted into KLRG1+ and KLRG1-.
 
Contributor(s) Newman D, Lun AT, Smyth GK
Citation(s) 27653692
Submission date Aug 08, 2016
Last update date May 15, 2019
Contact name Gordon K Smyth
E-mail(s) smyth@wehi.edu.au
Phone (+61 3) 9345 2326
Fax (+61 3) 9347 0852
URL http://www.wehi.edu.au
Organization name Walter and Eliza Hall Institute of Medical Research
Department Bioinformatics
Lab Smyth
Street address 1G Royal Pde
City Parkville
State/province Vic
ZIP/Postal code 3052
Country Australia
 
Platforms (1)
GPL13112 Illumina HiSeq 2000 (Mus musculus)
Samples (16)
GSM2264284 Kat6a-KO, KLRG1-low [1a]
GSM2264285 Kat6a-KO, KLRG1-high [1b]
GSM2264286 Wild-type, KLRG1-low [1c]
Relations
BioProject PRJNA338133
SRA SRP081081

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE85302_KAT6A-Tcell-GenewiseCounts.tsv.gz 551.8 Kb (ftp)(http) TSV
GSE85302_RAW.tar 2.7 Mb (http)(custom) TAR (of TSV)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file
Processed data are available on Series record

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